Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20127169 | 0.94 | MAPT (0.40) | MAPTSMN1; SMN2ALDH1A1HPGDKDM4E | |
| SCHEMBL20127175 | 0.93 | MAPT (0.38) | MAPTSMN1; SMN2ALDH1A1HPGDKDM4E | |
| SCHEMBL20127183 | 0.93 | MAPT (0.38) | MAPTSMN1; SMN2ALDH1A1HPGDKDM4E | |
| SCHEMBL22868719 | 0.91 | MAPT (0.34) | MAPTSMN1; SMN2ALDH1A1HPGDKDM4E | |
| SCHEMBL24307120 | 0.90 | MAPT (0.42) | MAPTSMN1; SMN2ALDH1A1HPGDKDM4E | |
| SCHEMBL22868875 | 0.90 | MEN1 (0.37) | MAPTSMN1; SMN2ALDH1A1HPGDKDM4E | |
| SCHEMBL22869076 | 0.89 | MEN1 (0.36) | MAPTSMN1; SMN2ALDH1A1HPGDKDM4E | |
| SCHEMBL22868947 | 0.89 | MEN1 (0.38) | MAPTSMN1; SMN2ALDH1A1HPGDKDM4E | |
| SCHEMBL22868717 | 0.88 | MAPT (0.34) | MAPTSMN1; SMN2ALDH1A1HPGDKDM4E | |
| SCHEMBL22868715 | 0.88 | CYP11B1 (0.33) | MAPTSMN1; SMN2ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10745362-B2 | Heterocyclic compound and organic light emitting device comprising same | LG CHEM, LTD. (KR) | 2020-08-18 | — | — | US | disclosed |
| US-20180127385-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME | LG CHEM LTD. (KR) | 2018-05-10 | — | — | US | disclosed |
| US-20180127385-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME | LG CHEM LTD. (KR) | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10745362-B2 | Heterocyclic compound and organic light emitting device comprising same | CRY1, CRY2, PER2 | MAPT 1073/4885SMN1; SMN2 4089/4885ALDH1A1 526/4885 |
| US-20180127385-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME | CRY1, CRY2, PER2 | MAPT 1073/4885SMN1; SMN2 4089/4885ALDH1A1 526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.