SCHEMBL20127348

SCHEMBL20127348

c1ccc(-c2ccc(-c3cc4oc5ccc(-c6c7ccccc7c(-c7ccc8ccccc8c7)c7ccccc67)cc5c4c4ccccc34)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
WEE1 P30291 1/20 0.40
PGR P06401 1/20 0.38
CYP1A2 P05177 2/20 0.38
CYP1A1 P04798 2/20 0.38
ABCG2 Q9UNQ0 2/20 0.38
FYN P06241 1/20 0.38
MAPK3 P27361 1/20 0.38
AHR P35869 1/20 0.38
PAX8 Q06710 1/20 0.38
KDM4E B2RXH2 4/20 0.38
ALDH1A1 P00352 3/20 0.38
MAPT P10636 3/20 0.38
HPGD P15428 3/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
MPI P34949 1/20 0.38
GPR84 Q9NQS5 3/20 0.38
PLA2G2A P14555 2/20 0.37
PLA2G4A P47712 2/20 0.37
ESR1 P03372 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20127356 0.99 WEE1 (0.41) WEE1PGRCYP1A2CYP1A1ABCG2
SCHEMBL20127351 0.93 GPR84 (0.40) WEE1CYP1A2CYP1A1ABCG2FYN
SCHEMBL20127353 0.90 GPR84 (0.38) PGRCYP1A2CYP1A1ABCG2FYN
SCHEMBL20127349 0.90 MAPT (0.39) CYP1A2CYP1A1ABCG2AHRKDM4E
SCHEMBL27334387 0.89 WEE1 (0.45) WEE1CYP1A2CYP1A1ABCG2AHR
SCHEMBL20127352 0.88 GPR84 (0.39) PGRCYP1A2CYP1A1ABCG2FYN
SCHEMBL20127394 0.88 PGR (0.42) PGRCYP1A2CYP1A1ABCG2FYN
SCHEMBL17931938 0.88 TDP1 (0.38) CYP1A2CYP1A1ABCG2ALDH1A1HPGD
SCHEMBL17944012 0.88 ABCG2 (0.47) PGRCYP1A2CYP1A1ABCG2FYN
SCHEMBL25023701 0.87 KDM4E (0.42) WEE1PGRCYP1A2CYP1A1ABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180208836-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180208836-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-05-10 US disclosed
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE RER1, NR0B1, NR2E1 WEE1 3100/4885PGR 1148/4885CYP1A2 821/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.