SCHEMBL20127679

SCHEMBL20127679

c1ccc2c(c1)oc1c(-c3c4ccccc4c(-c4cc5c6ccccc6oc5c5c4oc4ccccc45)c4ccccc34)cccc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.49
AHR P35869 1/20 0.41
PRKDC P78527 5/20 0.40
KDM4E B2RXH2 2/20 0.38
GAA P10253 2/20 0.38
HPGD P15428 2/20 0.38
HSD17B10 Q99714 2/20 0.38
MEN1 O00255 1/20 0.38
CYP3A4 P08684 1/20 0.38
ALPI P09923 1/20 0.38
MAPT P10636 1/20 0.38
PKM P14618 1/20 0.38
CASP3 P42574 1/20 0.38
RECQL P46063 1/20 0.38
BLM P54132 1/20 0.38
CASP7 P55210 1/20 0.38
CASP6 P55212 1/20 0.38
KMT2A Q03164 1/20 0.38
MCL1 Q07820 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10122691 0.92 AHR (0.46) ALOX5AHRKDM4EGAAHPGD
SCHEMBL20127694 0.90 ALOX5 (0.52) ALOX5AHRPRKDCKDM4EGAA
SCHEMBL20127700 0.89 ALOX5 (0.51) ALOX5AHRPRKDCKDM4EGAA
SCHEMBL10122247 0.88 ALOX5 (0.40) ALOX5AHRKDM4EGAAHPGD
SCHEMBL20127414 0.87 ALOX5 (0.54) ALOX5AHRPRKDCKDM4EHPGD
SCHEMBL10122234 0.87 CDC14B (0.41) ALOX5AHRKDM4EGAAHPGD
SCHEMBL10122243 0.86 AHR (0.41) ALOX5AHRKDM4EGAAHPGD
SCHEMBL27286954 0.86 ALOX5 (0.38) ALOX5AHRPRKDCKDM4EGAA
SCHEMBL26266634 0.85 ALOX5 (0.36) ALOX5AHRPRKDCKDM4EGAA
SCHEMBL9890833 0.85 ALOX5 (0.57) ALOX5AHRPRKDCKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180208836-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180208836-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-05-10 US disclosed
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE RER1, NR0B1, NR2E1 ALOX5 4115/4885AHR 2558/4885PRKDC 3891/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.