SCHEMBL20127700

SCHEMBL20127700

c1cc(-c2c3ccccc3c(-c3cc4c5ccccc5oc4c4c3oc3ccccc34)c3ccccc23)cc(-c2cccc3c2oc2ccccc23)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.51
GGPS1 O95749 1/20 0.44
PTGES2 Q9H7Z7 1/20 0.41
PRKDC P78527 7/20 0.39
CDC14B O60729 2/20 0.38
CDC14A Q9UNH5 2/20 0.38
PRMT5 O14744 1/20 0.36
WDR77 Q9BQA1 1/20 0.36
AHR P35869 1/20 0.35
ATM Q13315 1/20 0.34
KDM4E B2RXH2 2/20 0.34
GAA P10253 2/20 0.34
HSD17B10 Q99714 2/20 0.34
MEN1 O00255 1/20 0.34
CYP3A4 P08684 1/20 0.34
ALPI P09923 1/20 0.34
MAPT P10636 1/20 0.34
PKM P14618 1/20 0.34
HPGD P15428 1/20 0.34
CASP3 P42574 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20127694 0.91 ALOX5 (0.52) ALOX5GGPS1PTGES2PRKDCCDC14B
SCHEMBL10122236 0.91 PLA2G2A (0.40) ALOX5GGPS1PRKDCCDC14BCDC14A
SCHEMBL10122233 0.90 ALOX5 (0.40) ALOX5GGPS1PTGES2CDC14BCDC14A
SCHEMBL10122301 0.90 ALOX5 (0.42) ALOX5GGPS1PTGES2PRKDCCDC14B
SCHEMBL10122302 0.89 ALOX5 (0.43) ALOX5GGPS1PTGES2CDC14BCDC14A
SCHEMBL20127430 0.89 ALOX5 (0.56) ALOX5GGPS1PTGES2PRKDCPRMT5
SCHEMBL20127679 0.89 ALOX5 (0.49) ALOX5GGPS1PTGES2PRKDCAHR
SCHEMBL10122291 0.88 ALOX5 (0.42) ALOX5GGPS1PTGES2PRKDCCDC14B
SCHEMBL10122243 0.88 AHR (0.41) ALOX5GGPS1CDC14BCDC14AAHR
SCHEMBL15306303 0.88 ALOX5 (0.60) ALOX5GGPS1PTGES2PRKDCCDC14B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180208836-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180208836-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-05-10 US disclosed
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE RER1, NR0B1, NR2E1 ALOX5 4115/4885GGPS1 4058/4885PTGES2 4331/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.