SCHEMBL20127698

SCHEMBL20127698

c1cc(-c2ccc3c4ccccc4c4ccccc4c3c2)cc(-c2c3ccccc3c(-c3cc4c5ccccc5oc4c4c3oc3ccccc34)c3ccccc23)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 4/20 0.40
PLA2G4A P47712 4/20 0.40
PLA2G10 O15496 1/20 0.40
ALOX5 P09917 2/20 0.39
AHR P35869 2/20 0.35
CDC14B O60729 2/20 0.34
CDC14A Q9UNH5 2/20 0.34
KDM4E B2RXH2 2/20 0.33
GAA P10253 2/20 0.33
HSD17B10 Q99714 2/20 0.33
MEN1 O00255 2/20 0.33
MAPT P10636 2/20 0.33
KMT2A Q03164 2/20 0.33
CYP3A4 P08684 2/20 0.33
HPGD P15428 2/20 0.33
ALPI P09923 1/20 0.33
PKM P14618 1/20 0.33
CASP3 P42574 1/20 0.33
RECQL P46063 1/20 0.33
BLM P54132 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20127672 0.95 ALOX5 (0.39) PLA2G2APLA2G4APLA2G10ALOX5AHR
SCHEMBL20127697 0.93 PLA2G2A (0.42) PLA2G2APLA2G4APLA2G10ALOX5AHR
SCHEMBL21249194 0.93 ALOX5 (0.39) PLA2G2APLA2G4APLA2G10ALOX5AHR
SCHEMBL20127684 0.92 PLA2G2A (0.37) PLA2G2APLA2G4APLA2G10ALOX5AHR
SCHEMBL10122236 0.92 PLA2G2A (0.40) PLA2G2APLA2G4APLA2G10ALOX5AHR
SCHEMBL10122611 0.90 ALOX5 (0.41) PLA2G2APLA2G4APLA2G10ALOX5AHR
SCHEMBL20127427 0.88 ALOX5 (0.44) PLA2G2APLA2G4APLA2G10ALOX5AHR
SCHEMBL10122231 0.88 ALOX5 (0.37) PLA2G2APLA2G4APLA2G10ALOX5AHR
SCHEMBL10122260 0.87 PLA2G2A (0.41) PLA2G2APLA2G4APLA2G10ALOX5AHR
SCHEMBL23094345 0.87 PLA2G2A (0.35) PLA2G2APLA2G4APLA2G10ALOX5KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180208836-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180208836-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-07-26 US disclosed
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-05-10 US disclosed
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2018-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180130968-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE RER1, NR0B1, NR2E1 PLA2G2A 2960/4885PLA2G4A 3780/4885PLA2G10 4476/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.