Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.62 |
| ▸ | LYPLA2 | O95372 | 1/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.56 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.55 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA9 | Q16790 | 3/20 | 0.52 |
| ▸ | MAP1B | P46821 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | CD22 | P20273 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.45 |
| ▸ | TYK2 | P29597 | 1/20 | 0.45 |
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20127890 | 0.95 | SENP1 (0.63) | SENP1LYPLA2OPRM1SIRT2SETD7 | |
| SCHEMBL18694532 | 0.80 | OPRM1 (0.63) | SENP1LYPLA2OPRM1SIRT2CA12 | |
| SCHEMBL22473633 | 0.80 | OPRM1 (0.64) | SENP1LYPLA2OPRM1SIRT2CA12 | |
| SCHEMBL20896874 | 0.79 | OPRM1 (0.61) | SENP1LYPLA2OPRM1SIRT2CA12 | |
| SCHEMBL20896592 | 0.79 | OPRM1 (0.61) | SENP1LYPLA2OPRM1SIRT2CA12 | |
| SCHEMBL13735950 | 0.79 | OPRM1 (0.66) | SENP1LYPLA2OPRM1SIRT2CA12 | |
| SCHEMBL20904552 | 0.79 | CA12 (0.61) | SENP1LYPLA2OPRM1SIRT2CA12 | |
| SCHEMBL20896670 | 0.79 | CA12 (0.61) | SENP1LYPLA2OPRM1SIRT2CA12 | |
| SCHEMBL31578420 | 0.78 | OPRM1 (0.64) | SENP1LYPLA2OPRM1SIRT2SETD7 | |
| Hydrochloric Acid SCHEMBL20896828 | 0.78 | OPRM1 (0.60) | SENP1LYPLA2OPRM1SIRT2SETD7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180127358-A1 | ANTI-INFLAMMATORY DRUG AND USES THEREOF | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2018-05-10 | — | — | US | disclosed |
| US-20180127358-A1 | ANTI-INFLAMMATORY DRUG AND USES THEREOF | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180127358-A1 | ANTI-INFLAMMATORY DRUG AND USES THEREOF | CDK2, CCNT2, CCNE2 | SENP1 943/4885LYPLA2 962/4885OPRM1 2347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.