Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 3/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CCR9 | P51686 | 1/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2015150 | 0.82 | MEN1 (0.40) | ACHEBCHECYP17A1CYP19A1MEN1 | |
| SCHEMBL3685854 | 0.79 | HPGD (0.32) | CYP17A1CYP19A1KCNA3 | |
| SCHEMBL2014595 | 0.78 | MGAM (0.32) | — | |
| SCHEMBL3006033 | 0.78 | CYP1A2 (0.34) | CYP17A1CYP19A1MEN1KMT2A | |
| SCHEMBL2015640 | 0.78 | ALDH1A1 (0.39) | CYP17A1CYP19A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2012828 | 0.77 | CCR9 (0.34) | TACR1ACHEBCHEBACE1CCR9 | |
| SCHEMBL289717 | 0.76 | OPRK1 (0.42) | HSD11B1MEN1KMT2A | |
| Bromide SCHEMBL1478373 | 0.75 | OPRK1 (0.41) | HSD11B1MEN1KMT2A | |
| SCHEMBL5738047 | 0.75 | OPRK1 (0.41) | HSD11B1MEN1KMT2A | |
| SCHEMBL2995855 | 0.73 | CYP17A1 (0.32) | CYP17A1CYP19A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2513031-A1 | A CONTINUOUS PROCESS FOR THE CARBONYLATION OF ETHYLENE | Lucite International UK Limited (GB) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011073655-A1 | A CONTINUOUS PROCESS FOR THE CARBONYLATION OF ETHYLENE | LUCITE INTERNATIONAL UK LIMITED (GB) | 2011-06-23 | — | — | WO | disclosed |