SCHEMBL289717

SCHEMBL289717

c1ccc(CP(C23CC4CC(CC(C4)C2)C3)C23CC4CC(CC(C4)C2)C3)cc1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
OPRK1 P41145 1/20 0.42
ALDH1A1 P00352 1/20 0.42
TSHR P16473 1/20 0.42
HPGD P15428 1/20 0.42
CHRM2 P08172 1/20 0.42
CHRM4 P08173 1/20 0.42
CHRM5 P08912 1/20 0.42
EPHX2 P34913 4/20 0.41
P2RX7 Q99572 3/20 0.41
MAPK1 P28482 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
HSD11B1 P28845 3/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL1478373 0.98 OPRK1 (0.41) OPRK1ALDH1A1TSHRHPGDCHRM2
SCHEMBL5738047 0.98 OPRK1 (0.41) OPRK1ALDH1A1TSHRHPGDCHRM2
SCHEMBL2011475 0.90 HPGD (0.39) OPRK1ALDH1A1TSHRHPGDEPHX2
SCHEMBL15659951 0.85 ALDH1A1 (0.42) OPRK1ALDH1A1TSHRHPGDCHRM2
SCHEMBL2015640 0.84 ALDH1A1 (0.39) OPRK1ALDH1A1TSHRHPGDP2RX7
SCHEMBL1734830 0.82 P2RX7 (0.39) OPRK1ALDH1A1TSHRHPGDEPHX2
SCHEMBL6465665 0.82 EPHX2 (0.33) OPRK1ALDH1A1TSHRHPGDEPHX2
SCHEMBL21562234 0.82 HSD11B1 (0.37) OPRK1ALDH1A1TSHRHPGDCHRM2
SCHEMBL2830096 0.81 P2RX7 (0.38) OPRK1ALDH1A1TSHRHPGDEPHX2
SCHEMBL16573840 0.80 EPHX2 (0.38) OPRK1ALDH1A1TSHRHPGDCHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 212 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2427468-B2 PREPARATION OF A METAL COMPLEX JOHNSON MATTHEY PLC (GB) 2025-06-04 EP claimed
CN-118420533-A Method for synthesizing isoquinolinone by carbonylation of aryl alkyne and hydroxylamine 中国科学技术大学 2024-08-02 CN claimed
EP-4267591-A2 ORGANOMETALLIC COMPOUNDS Umicore AG & Co. KG (DE) 2023-11-01 EP claimed
CN-116802187-A Organometallic compounds 优米科尔股份公司及两合公司 2023-09-22 CN claimed
CN-116655587-A Preparation method of suprofen 酒泉职业技术学院(甘肃广播电视大学酒泉市分校) 2023-08-29 CN claimed
CN-116082157-A Method for preparing organic carboxylic ester by olefine unsaturated compound alkoxycarbonyl reaction 上海梓龄化工技术有限公司 2023-05-09 CN claimed
WO-2022136049-A2 ORGANOMETALLIC COMPOUNDS UMICORE AG & CO. KG (DE) 2022-06-30 WO claimed
EP-3369723-B1 METHOD FOR MANUFACTURING ARYL AND HETEROARYL ACETIC ACID DERIVATIVES BAYER CROPSCIENCE AG (DE) 2020-10-14 EP claimed
CN-106928061-B Continuous process for the carbonylation of ethylene 璐彩特国际英国有限公司 2020-08-28 CN claimed
EP-3369723-A1 METHOD FOR MANUFACTURING ARYL AND HETEROARYL ACETIC ACID DERIVATIVES Bayer CropScience Aktiengesellschaft (DE) 2018-09-05 EP claimed
WO-2010128316-A1 PREPARATION OF A METAL COMPLEX JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2010-11-11 WO claimed
EP-1303525-B1 PRODUCTION OF NOVEL PHOSPHANE LIGANDS AND USE IN CATALYTICAL REACTIONS EVONIK DEGUSSA GMBH (DE) 2010-09-08 EP claimed
US-20100022780-A1 PROCESS FOR PREPARING 2-AMINO-5-CYANOBENZOIC ACID DERIVATIVES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-01-28 US claimed
EP-2102150-A1 PROCESS FOR PREPARING 2-AMINO-5-CYANOBENZOIC ACID DERIVATIVES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-09-23 EP claimed
WO-2008070158-A1 PROCESS FOR PREPARING 2-AMINO-5-CYANOBENZOIC ACID DERIVATIVES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-06-12 WO claimed
EP-1748976-A1 ALKOXYCARBONYLATION OF VINYL ESTERS Lucite International UK Limited (GB) 2007-02-07 EP claimed
WO-2005118519-A1 ALKOXYCARBONYLATION OF VYNIL ESTERS LUCITE INTERNATIONAL UK LTD (GB) 2005-12-15 WO claimed
JP-2005535695-A 2005-11-24 JP claimed
EP-1527038-A1 PROCESS FOR THE CARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUDS Lucite International UK Limited (GB) 2005-05-04 EP claimed
WO-2004014834-A1 PROCESS FOR THE CARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUDS LUCITE INTERNATIONAL UK LIMITED (GB) 2004-02-19 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100022780-A1 PROCESS FOR PREPARING 2-AMINO-5-CYANOBENZOIC ACID DERIVATIVES PRMT6, C5, CHRM1 OPRK1 2221/4885ALDH1A1 756/4885TSHR 1137/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.