Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.48 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.48 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PDE11A | Q9HCR9 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7331482 | 0.84 | IDO1 (0.56) | ALDH1A1KDM4ETP53SMN1; SMN2MAPT | |
| SCHEMBL20549125 | 0.84 | ALDH1A1 (0.41) | ALDH1A1KDM4ETP53SMN1; SMN2MAPT | |
| SCHEMBL18747058 | 0.82 | PARP10 (0.51) | ALDH1A1KDM4ESMN1; SMN2MAPTPARP15 | |
| SCHEMBL20128397 | 0.81 | TP53 (0.55) | ALDH1A1KDM4ETP53SMN1; SMN2MAPT | |
| SCHEMBL7331806 | 0.79 | TP53 (0.52) | ALDH1A1KDM4ETP53SMN1; SMN2MAPT | |
| SCHEMBL7336368 | 0.79 | TP53 (0.49) | ALDH1A1KDM4ETP53SMN1; SMN2MAPT | |
| SCHEMBL20549080 | 0.79 | KDM4E (0.46) | ALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL20549093 | 0.77 | MAPT (0.42) | ALDH1A1KDM4ETP53SMN1; SMN2MAPT | |
| SCHEMBL20549028 | 0.76 | MAPT (0.49) | ALDH1A1KDM4ETP53SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL20549074 | 0.76 | MAPT (0.41) | ALDH1A1KDM4ETP53SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10227361-B2 | Fused imidazobenzothiazole compounds | TORRENT PHARMACEUTICALS LIMITED (IN) | 2019-03-12 | — | — | US | disclosed |
| US-20180127437-A1 | NOVEL FUSED IMIDAZOBENZOTHIAZOLE COMPOUNDS | TORRENT PHARMACEUTICALS LIMITED (IN) | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180127437-A1 | NOVEL FUSED IMIDAZOBENZOTHIAZOLE COMPOUNDS | CYP3A5, CYP11B2, CYP3A4 | ALDH1A1 2526/4885KDM4E 4213/4885TP53 2728/4885 |
| US-10227361-B2 | Fused imidazobenzothiazole compounds | IPO4, CYP3A5, CYP3A4 | ALDH1A1 2806/4885KDM4E 4381/4885TP53 1312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.