Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | THRB | P10828 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.37 |
| ▸ | ACR | P10323 | 2/20 | 0.37 |
| ▸ | RARA | P10276 | 2/20 | 0.37 |
| ▸ | RARB | P10826 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20126276 | 0.86 | THRB (0.40) | MAPTTHRBSMN1; SMN2KMT2APLA2G1B | |
| SCHEMBL20129323 | 0.84 | LMNA (0.47) | MAPTSMN1; SMN2KMT2ARAB9APRSS1 | |
| SCHEMBL20128405 | 0.80 | SPHK1 (0.35) | RARB | |
| SCHEMBL11300563 | 0.80 | MAPT (0.53) | MAPTTHRBSMN1; SMN2KMT2APLA2G1B | |
| SCHEMBL11412641 | 0.79 | MAPT (0.46) | MAPTTHRBSMN1; SMN2KMT2APLA2G1B | |
| SCHEMBL11412615 | 0.79 | MAPT (0.46) | MAPTTHRBSMN1; SMN2KMT2APLA2G1B | |
| SCHEMBL10633416 | 0.78 | THRB (0.62) | MAPTTHRBSMN1; SMN2KMT2APLA2G1B | |
| SCHEMBL30354554 | 0.78 | THRB (0.62) | MAPTTHRBSMN1; SMN2KMT2APLA2G1B | |
| SCHEMBL11412000 | 0.78 | CYP2C9 (0.46) | MAPTTHRBSMN1; SMN2KMT2APLA2G1B | |
| SCHEMBL11411710 | 0.78 | CYP2C9 (0.46) | MAPTTHRBSMN1; SMN2KMT2APLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180127654-A1 | PIPERIDINE DERIVATIVE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180127654-A1 | PIPERIDINE DERIVATIVE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | DRD1, PLD1, DRD2 | MAPT 3166/4885THRB 3896/4885SMN1; SMN2 4549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.