Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.81 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.81 |
| ▸ | PDE2A | O00408 | 1/20 | 0.81 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.81 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.81 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.81 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.81 |
| ▸ | LMNA | P02545 | 2/20 | 0.78 |
| ▸ | TP53 | P04637 | 1/20 | 0.78 |
| ▸ | NT5E | P21589 | 1/20 | 0.75 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.75 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.73 |
| ▸ | CA1 | P00915 | 1/20 | 0.72 |
| ▸ | CA2 | P00918 | 1/20 | 0.72 |
| ▸ | CA4 | P22748 | 1/20 | 0.72 |
| ▸ | CA9 | Q16790 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6837087 | 1.00 | ADORA3 (0.81) | ADORA3ADORA2APDE2AADORA1ADRA1A | |
| SCHEMBL19953842 | 1.00 | ADORA3 (0.81) | ADORA3ADORA2APDE2AADORA1ADRA1A | |
| SCHEMBL1663268 | 1.00 | ADORA3 (0.81) | ADORA3ADORA2APDE2AADORA1ADRA1A | |
| SCHEMBL13863559 | 1.00 | ADORA3 (0.81) | ADORA3ADORA2APDE2AADORA1ADRA1A | |
| SCHEMBL104095 | 1.00 | ADORA3 (0.81) | ADORA3ADORA2APDE2AADORA1ADRA1A | |
| SCHEMBL104094 | 1.00 | ADORA3 (0.81) | ADORA3ADORA2APDE2AADORA1ADRA1A | |
| SCHEMBL1389446 | 1.00 | ADORA3 (0.81) | ADORA3ADORA2APDE2AADORA1ADRA1A | |
| SCHEMBL397323 | 1.00 | ADORA3 (0.81) | ADORA3ADORA2APDE2AADORA1ADRA1A | |
| SCHEMBL6886946 | 1.00 | ADORA3 (0.81) | ADORA3ADORA2APDE2AADORA1ADRA1A | |
| SCHEMBL4535914 | 1.00 | ADORA3 (0.81) | ADORA3ADORA2APDE2AADORA1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10392417-B2 | Polymorph of regadenoson and process for preparation thereof | APICORE US LLC (US) | 2019-08-27 | — | — | US | disclosed |
| US-20180127452-A1 | NOVEL POLYMORPH OF REGADENOSON AND PROCESS FOR PREPARATION THEREOF | APICORE US LLC (US) | 2018-05-10 | — | — | US | disclosed |
| US-20180127452-A1 | NOVEL POLYMORPH OF REGADENOSON AND PROCESS FOR PREPARATION THEREOF | APICORE US LLC (US) | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180127452-A1 | NOVEL POLYMORPH OF REGADENOSON AND PROCESS FOR PREPARATION THEREOF | PRPF6, CYP2D6, ADH1A | ADORA3 674/4885ADORA2A 873/4885PDE2A 1095/4885 |
| US-10392417-B2 | Polymorph of regadenoson and process for preparation thereof | CYP2D6, PRPF6, CYP2B6 | ADORA3 553/4885ADORA2A 702/4885PDE2A 1060/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.