Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.53 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.53 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.53 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 3/20 | 0.53 |
| ▸ | MMP1 | P03956 | 2/20 | 0.53 |
| ▸ | MMP3 | P08254 | 2/20 | 0.53 |
| ▸ | MMP7 | P09237 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | PREP | P48147 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.49 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20129643 | 0.91 | PARP1 (0.55) | SMN1; SMN2NPC1RAB9APDK1PDK2 | |
| SCHEMBL13681760 | 0.91 | PARP1 (0.55) | SMN1; SMN2NPC1RAB9APDK1PDK2 | |
| SCHEMBL6487540 | 0.91 | PDK1 (0.53) | SMN1; SMN2NPC1RAB9APDK1PDK2 | |
| SCHEMBL1288345 | 0.91 | PDK1 (0.53) | SMN1; SMN2NPC1RAB9APDK1PDK2 | |
| SCHEMBL15298945 | 0.91 | PDK1 (0.53) | SMN1; SMN2NPC1RAB9APDK1PDK2 | |
| SCHEMBL2820733 | 0.91 | PARP1 (0.55) | SMN1; SMN2NPC1RAB9APDK1PDK2 | |
| SCHEMBL19120482 | 0.89 | PDK1 (0.52) | SMN1; SMN2NPC1RAB9APDK1PDK2 | |
| SCHEMBL15298942 | 0.89 | FKBP1A (0.51) | SMN1; SMN2NPC1RAB9APDK1PDK2 | |
| SCHEMBL6141635 | 0.89 | FKBP1A (0.51) | SMN1; SMN2NPC1RAB9APDK1PDK2 | |
| SCHEMBL7802196 | 0.88 | POLB (0.52) | SMN1; SMN2NPC1RAB9AHTTPREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955460-A | EFFECTIVE AGAINST INFECTIONS CAUSED BY ANTIBIOTIC RESISTANT BACTERIA | PHARMACIA & UPJOHN COMPANY (US) | 1999-09-21 | — | — | US | disclosed |
| US-5922707-A | Oxazolidinone antibacterial agent with tricyclic substituents | PHARMACIA & UPJOHN COMPANY (US) | 1999-07-13 | — | — | US | disclosed |