SCHEMBL2013010

SCHEMBL2013010

O=C(O)OCCC1=NOC(c2ccccc2)(c2ccc(F)cc2)C1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 1/20 0.38
POLB P06746 1/20 0.35
GAA P10253 1/20 0.35
SSTR5 P35346 1/20 0.34
PTGS2 P35354 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
HSD11B1 P28845 4/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CHRM5 P08912 1/20 0.33
CHRM1 P11229 1/20 0.33
OPRD1 P41143 1/20 0.32
CACNA1H O95180 2/20 0.32
CACNA1C Q13936 2/20 0.32
DRD2 P14416 1/20 0.32
EGFR P00533 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27617076 0.84 PTGDR2 (0.34) PTGDR2POLBGAAMEN1KMT2A
SCHEMBL23930213 0.78 PTGDR2 (0.34) PTGDR2POLBGAASSTR5NPSR1
SCHEMBL27935323 0.76
SCHEMBL28401713 0.75 LMNA (0.42) PTGDR2MEN1KMT2ACHRM5CHRM1
SCHEMBL1832298 0.75 PTGDR2 (0.38) PTGDR2POLBGAAPTGS2HSD11B1
SCHEMBL342177 0.75 MAPT (0.43) GAANPSR1MEN1KMT2AOPRD1
SCHEMBL28044294 0.74 SMN1; SMN2 (0.44) PTGDR2
SCHEMBL165837 0.74 OPRD1 (0.39) PTGDR2POLBGAAMEN1KMT2A
SCHEMBL27935387 0.71
SCHEMBL2467015 0.70 NPY5R (0.38) PTGDR2POLBGAAPTGS2ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2693878-A1 SUBSTITUTED (3R,4R)-4-CYAN-3,4-DIPHENYLBUTANOATES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS Bayer Intellectual Property GmbH (DE) 2014-02-12 EP disclosed
WO-2012126765-A1 SUBSTITUTED (3R,4R)-4-CYAN-3,4-DIPHENYLBUTANOATES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS BAYER CROPSCIENCE AG (DE) 2012-09-27 WO disclosed
WO-2011073098-A1 1-(HETEROARYL)-PYRAZOL-4-YL-ACETIC ACIDS, METHOD FOR THE PRODUCTION THEREOF, AND THE USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS BAYER CROPSCIENCE AG (DE) 2011-06-23 WO disclosed