SCHEMBL342177

SCHEMBL342177

CCOC(=O)C1=NOC(c2ccccc2)(c2ccc(F)cc2)C1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.43
KDM4E B2RXH2 4/20 0.43
KMT2A Q03164 2/20 0.43
RECQL P46063 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
CRHBP P24387 1/20 0.43
CRHR2 Q13324 1/20 0.43
ALDH1A1 P00352 7/20 0.40
OPRD1 P41143 1/20 0.40
GAA P10253 3/20 0.39
LMNA P02545 2/20 0.39
OPRM1 P35372 1/20 0.39
HSD17B10 Q99714 1/20 0.39
ELANE P08246 1/20 0.38
NPSR1 Q6W5P4 2/20 0.38
HPGD P15428 2/20 0.38
MEN1 O00255 1/20 0.38
ALOX12 P18054 1/20 0.38
CCR6 P51684 1/20 0.38
HKDC1 Q2TB90 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7640011 0.93 MAPT (0.47) MAPTKDM4EKMT2ARECQLTDP1
SCHEMBL124147 0.93 MAPT (0.47) MAPTKDM4EKMT2ARECQLTDP1
SCHEMBL28401713 0.91 LMNA (0.42) MAPTKDM4EKMT2ARECQLTDP1
SCHEMBL17584752 0.89 ALDH1A1 (0.41) MAPTKDM4EKMT2ARECQLTDP1
SCHEMBL6051256 0.87 LMNA (0.44) MAPTKDM4EKMT2ARECQLTDP1
SCHEMBL694567 0.83 LMNA (0.48) MAPTKDM4EKMT2ARECQLTDP1
SCHEMBL165837 0.82 OPRD1 (0.39) KMT2AOPRD1GAAOPRM1MEN1
SCHEMBL1832298 0.82 PTGDR2 (0.38) KMT2AGAAMEN1
SCHEMBL15227259 0.79 ALDH1A1 (0.40) MAPTKDM4EKMT2AALDH1A1OPRD1
SCHEMBL29205863 0.78 MAPT (0.46) MAPTKDM4EKMT2ARECQLTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1053 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113367128-A Composition containing R-type oxadiazolyl aryl formamide compound and safener and application thereof 江苏清原农冠杂草防治有限公司 2021-09-10 CN claimed
EP-2099751-B1 BIPHENYL-SUBSTITUTED SPIROCYCLIC KETOENOLS BAYER IP GMBH (DE) 2018-05-30 EP claimed
US-20160000076-A1 Fungicidal Active Compound Combinations BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-01-07 US claimed
EP-2185563-B1 OXASPIROCYCLIC SPIRO-SUBSTITUTED TETRAMIC AND TETRONIC ACID DERIVATIVES BAYER IP GMBH (DE) 2015-08-19 EP claimed
EP-1943218-B1 ALKOXYALKYL SPIROCYCLIC TETRAMIC ACIDS AND TETRONIC ACIDS BAYER IP GMBH (DE) 2015-05-06 EP claimed
US-8993782-B2 Cis-alkoxyspirocyclic biphenyl-substituted tetramic acid derivatives BAYER CROPSCIENCE AG (DE) 2015-03-31 US claimed
EP-2195290-B1 HALOGEN ALKOXY SPIROCYCLIC TETRAMIC AND TETRONIC ACID DERIVATIVES BAYER IP GMBH (DE) 2015-03-11 EP claimed
US-8901036-B2 Combinations of phenylsulfonylurea herbicides and safeners BAYER CROPSCIENCE AG (DE) 2014-12-02 US claimed
EP-1771067-B1 SELECTIVE INSECTICIDES BASED ON SUBSTITUTED, CYCLIC KETO-ENOLS AND SAFENERS BAYER CROPSCIENCE AG (DE) 2014-03-12 EP claimed
US-8629084-B2 Iodine-phenyl-substituted cyclic cetoenols BAYER CROPSCIENCE AG (DE) 2014-01-14 US claimed
US-20050009705-A1 Selective herbicides based on substituted thien-3-yl-sulfonylamino(thio)carbonyltriazolin(thi)ones and safeners BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2005-01-13 US claimed
CN-1564660-A Selective herbicides based on substituted cyclic ketoenols and safeners BAYER CROPSCIENCE AG (DE) 2005-01-12 CN claimed
CN-1555221-A Selective herbicides based on substituted thien-3-yl-sulfonylamino(thio)carbonyl-triazolin(thi)ones and safeners �ݶ�ũ�����ѧ�ɷݹ�˾ 2004-12-15 CN claimed
CN-1543311-A Selective substituted aryl ketone and safener based herbicides 拜尔农作物科学股份公司 2004-11-03 CN claimed
US-20040157737-A1 For protecting crop plants from phytotoxic side effects of herbicides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2004-08-12 US claimed
US-20040132619-A1 Selective substituted aryl ketone and safener based herbicides BAYER CROPSCIENCE K.K. (JP) 2004-07-08 US claimed
WO-2003103394-A2 COMBINATIONS OF HERBICIDAL AROMATIC CARBOXYLIC ACIDS AND SAFENERS BAYER CROPSCIENCE GMBH (DE) 2003-12-18 WO claimed
US-20030232725-A1 Combinations of herbicidal aromatic carboxylic acids and safeners BAYER CROPSCIENCE AG (DE) 2003-12-18 US claimed
US-20030211942-A1 Aryl sulfonyl amino carbonyl triazole based selective herbicides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2003-11-13 US claimed
US-6124240-A Combinations of sulfonylurea herbicides and safeners HOECHST AGREVO GMBH (DE) 2000-09-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030211942-A1 Aryl sulfonyl amino carbonyl triazole based selective herbicides AADAC, CBR3, ABAT MAPT 3907/4885KDM4E 1867/4885KMT2A 462/4885
US-20040132619-A1 Selective substituted aryl ketone and safener based herbicides CYP2W1, CYP4Z1, CYP2E1 MAPT 4513/4885KDM4E 1001/4885KMT2A 498/4885
US-20050009705-A1 Selective herbicides based on substituted thien-3-yl-sulfonylamino(thio)carbonyltriazolin(thi)ones and safeners TARS2, TST, DDT MAPT 2742/4885KDM4E 2555/4885KMT2A 655/4885
US-20030232725-A1 Combinations of herbicidal aromatic carboxylic acids and safeners DDT, CYP2W1, AADAC MAPT 4556/4885KDM4E 3880/4885KMT2A 1645/4885
US-20160000076-A1 Fungicidal Active Compound Combinations DDT, CYP4X1, CYP51A1 MAPT 4650/4885KDM4E 2075/4885KMT2A 1264/4885
US-20040157737-A1 For protecting crop plants from phytotoxic side effects of herbicides GSTO1, CYP1A1, HAO2 MAPT 4392/4885KDM4E 2788/4885KMT2A 838/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.