SCHEMBL201302

SCHEMBL201302

CCCCCCOc1cccc(C(N)=O)c1F

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.74
CYP3A4 P08684 2/20 0.74
MEN1 O00255 1/20 0.74
NR1I2 O75469 1/20 0.74
CHRM2 P08172 1/20 0.74
ADRA2A P08913 1/20 0.74
MAPT P10636 1/20 0.74
OPRK1 P41145 1/20 0.74
HTR2B P41595 1/20 0.74
SLC6A3 Q01959 1/20 0.74
KMT2A Q03164 1/20 0.74
HDAC6 Q9UBN7 1/20 0.74
PTPN1 P18031 2/20 0.50
CNR1 P21554 2/20 0.48
CNR2 P34972 2/20 0.48
ALDH1A1 P00352 2/20 0.48
TSHR P16473 2/20 0.48
HTT P42858 1/20 0.47
CYP2C9 P11712 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL201322 1.00 LMNA (0.74) LMNACYP3A4MEN1NR1I2CHRM2
SCHEMBL12433060 1.00 LMNA (0.74) LMNACYP3A4MEN1NR1I2CHRM2
SCHEMBL4567020 0.85 LMNA (0.52) LMNACYP3A4MEN1NR1I2CHRM2
Exalamide SCHEMBL151112 0.85 LMNA (1.00) LMNACYP3A4MEN1NR1I2CHRM2
SCHEMBL5147507 0.85 LMNA (1.00) LMNACYP3A4MEN1NR1I2CHRM2
SCHEMBL874312 0.85 LMNA (1.00) LMNACYP3A4MEN1NR1I2CHRM2
SCHEMBL4656110 0.85 LMNA (1.00) LMNACYP3A4MEN1NR1I2CHRM2
SCHEMBL873025 0.85 LMNA (1.00) LMNACYP3A4MEN1NR1I2CHRM2
SCHEMBL9417650 0.85 LMNA (1.00) LMNACYP3A4MEN1NR1I2CHRM2
SCHEMBL29603307 0.85 LMNA (1.00) LMNACYP3A4MEN1NR1I2CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102008459-B Antibacterial agents BIOTA SCIENT MAN 2013-05-29 CN claimed
US-20250179008-A1 ANTIBACTERIAL AGENTS TAXIS PHARMACEUTICALS, INC. (US) 2025-06-05 US disclosed
US-20150191420-A1 ANTIBACTERIAL AGENTS TAXIS PHARMACEUTICALS, INC. 2015-07-09 US disclosed
US-20150191420-A1 ANTIBACTERIAL AGENTS TAXIS PHARMACEUTICALS, INC. 2015-07-09 US disclosed
US-20150191420-A1 ANTIBACTERIAL AGENTS TAXIS PHARMACEUTICALS, INC. 2015-07-09 US disclosed
US-8865736-B2 Antibacterial agents Biota Scientific Pty Ltd (AU) 2014-10-21 US disclosed
US-8865736-B2 Antibacterial agents Biota Scientific Pty Ltd (AU) 2014-10-21 US disclosed
US-8865736-B2 Antibacterial agents Biota Scientific Pty Ltd (AU) 2014-10-21 US disclosed
CN-102008459-B Antibacterial agents BIOTA SCIENT MAN 2013-05-29 CN disclosed
US-20130072520-A2 ANTIBACTERIAL AGENTS BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2013-03-21 US disclosed
CN-101404989-B Antibacterial agent PROLYSIS LTD 2011-10-05 CN disclosed
EP-1996180-B1 BENZAMIDE AND PYRIDYLAMIDE DERIVATIVES AS ANTIBACTERIAL AGENTS BIOTA EUROPE LTD (GB) 2011-08-03 EP disclosed
EP-1996180-B1 BENZAMIDE AND PYRIDYLAMIDE DERIVATIVES AS ANTIBACTERIAL AGENTS BIOTA EUROPE LTD (GB) 2011-08-03 EP disclosed
CN-102008459-A Antibacterial agents PROLYSIS LTD 2011-04-13 CN disclosed
US-20100173933-A1 ANTIBACTERIAL AGENTS PROLYSIS LTD (GB) 2010-07-08 US disclosed
US-20100173933-A1 ANTIBACTERIAL AGENTS PROLYSIS LTD (GB) 2010-07-08 US disclosed
CN-101404989-A Antibacterial agent PROLYSIS LTD (GB) 2009-04-08 CN disclosed
EP-1996180-A1 ANTIBACTERIAL AGENTS Prolysis Limited (GB) 2008-12-03 EP disclosed
WO-2007107758-A1 ANTIBACTERIAL AGENTS PROLYSIS LTD (GB) 2007-09-27 WO disclosed
WO-2007107758-A1 ANTIBACTERIAL AGENTS PROLYSIS LTD (GB) 2007-09-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130072520-A2 ANTIBACTERIAL AGENTS ALK, ROS1, NOX1 LMNA 1817/4885CYP3A4 795/4885MEN1 678/4885
US-20150191420-A1 ANTIBACTERIAL AGENTS ALK, ARG1, ROS1 LMNA 2877/4885CYP3A4 1699/4885MEN1 1027/4885
US-20250179008-A1 ANTIBACTERIAL AGENTS ALK, ROS1, NOX1 LMNA 1817/4885CYP3A4 795/4885MEN1 678/4885
US-20100173933-A1 ANTIBACTERIAL AGENTS ALK, ROS1, NOX1 LMNA 1817/4885CYP3A4 795/4885MEN1 678/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.