Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19363749 | 0.83 | HPGD (0.47) | HPGDLMNAALDH1A1GAA | |
| SCHEMBL20130270 | 0.80 | HRH3 (0.49) | HRH3HPGDLMNAALDH1A1GAA | |
| SCHEMBL21166392 | 0.77 | LMNA (0.56) | HPGDLMNAALDH1A1GAA | |
| SCHEMBL10024623 | 0.76 | HRH3 (0.39) | HRH3HPGDALDH1A1GAA | |
| SCHEMBL8377574 | 0.75 | HRH3 (0.59) | HRH3 | |
| SCHEMBL14157744 | 0.75 | HRH3 (0.59) | HRH3 | |
| SCHEMBL17368484 | 0.74 | LMNA (0.33) | HPGDLMNAALDH1A1GAA | |
| SCHEMBL20130240 | 0.74 | HRH3 (0.43) | HRH3LMNAGAA | |
| SCHEMBL20287613 | 0.73 | ALDH1A1 (0.45) | HRH3HPGDLMNAALDH1A1 | |
| SCHEMBL8684475 | 0.73 | HRH3 (0.50) | HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180126011-A1 | DENDRI-TAC AND THEIR USE AS THERANOSTICS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180126011-A1 | DENDRI-TAC AND THEIR USE AS THERANOSTICS | DBI, CDIPT, DGKI | HRH3 4522/4885HPGD 3858/4885LMNA 2780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.