Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCD1 | P51178 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.39 |
| ▸ | RNF168 | Q8IYW5 | 1/20 | 0.39 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | FLI1 | Q01543 | 1/20 | 0.37 |
| ▸ | EWSR1 | Q01844 | 1/20 | 0.37 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.37 |
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
| ▸ | FGF1 | P05230 | 1/20 | 0.37 |
| ▸ | FGF2 | P09038 | 1/20 | 0.37 |
| ▸ | VEGFA | P15692 | 1/20 | 0.37 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20130674 | 0.88 | PLCD1 (0.43) | PLCD1TDP1F2PRSS1PRSS2 | |
| SCHEMBL20130787 | 0.85 | PLCD1 (0.48) | PLCD1TDP1F2PRSS1PRSS2 | |
| SCHEMBL19647020 | 0.80 | PLCD1 (0.53) | PLCD1TDP1F2PRSS1PRSS2 | |
| SCHEMBL22192982 | 0.79 | PLCD1 (0.46) | PLCD1TDP1F2PRSS1PRSS2 | |
| SCHEMBL10433089 | 0.78 | PLCD1 (0.41) | PLCD1TDP1F2RNF168 | |
| SCHEMBL20129628 | 0.78 | FGF1 (0.51) | PLCD1TDP1F2PRSS1PRSS2 | |
| SCHEMBL20129498 | 0.78 | FGF1 (0.51) | PLCD1TDP1F2PRSS1PRSS2 | |
| SCHEMBL19647035 | 0.77 | TDP1 (0.46) | PLCD1TDP1F2PRSS1PRSS2 | |
| SCHEMBL30763662 | 0.76 | PLCD1 (0.44) | PLCD1TDP1F2PRSS1PRSS2 | |
| SCHEMBL29592014 | 0.76 | PLCD1 (0.44) | PLCD1TDP1F2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10683531-B2 | Methods of nucleic acid sample preparation for analysis of cell-free DNA | ArcherDX, Inc. (US) | 2020-06-16 | — | — | US | disclosed |
| US-20180127807-A1 | METHODS OF NUCLEIC ACID SAMPLE PREPARATION FOR ANALYSIS OF CELL-FREE DNA | ArcherDX, Inc. (US) | 2018-05-10 | — | — | US | disclosed |