Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGF1 | P05230 | 1/20 | 0.51 |
| ▸ | FGF2 | P09038 | 1/20 | 0.51 |
| ▸ | VEGFA | P15692 | 1/20 | 0.51 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HINT1 | P49773 | 1/20 | 0.47 |
| ▸ | PLCD1 | P51178 | 1/20 | 0.43 |
| ▸ | HLCS | P50747 | 2/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
| ▸ | RNF168 | Q8IYW5 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20129498 | 1.00 | FGF1 (0.51) | FGF1FGF2VEGFAHPSETDP1 | |
| SCHEMBL19647035 | 0.88 | TDP1 (0.46) | FGF1FGF2VEGFAHPSETDP1 | |
| SCHEMBL19647020 | 0.86 | PLCD1 (0.53) | FGF1FGF2VEGFAHPSETDP1 | |
| SCHEMBL12937940 | 0.81 | FOLH1 (0.50) | FGF1FGF2VEGFAHPSETDP1 | |
| SCHEMBL12253297 | 0.81 | FOLH1 (0.50) | FGF1FGF2VEGFAHPSETDP1 | |
| SCHEMBL12937921 | 0.81 | FOLH1 (0.50) | FGF1FGF2VEGFAHPSETDP1 | |
| SCHEMBL12230448 | 0.81 | FOLH1 (0.50) | FGF1FGF2VEGFAHPSETDP1 | |
| SCHEMBL20130787 | 0.81 | PLCD1 (0.48) | FGF1FGF2VEGFAHPSETDP1 | |
| SCHEMBL13844235 | 0.79 | FGF1 (0.46) | FGF1FGF2VEGFAHPSETDP1 | |
| SCHEMBL20130786 | 0.78 | PLCD1 (0.44) | FGF1FGF2VEGFAHPSETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180127822-A1 | MODIFIED NUCLEOTIDES METHODS AND KITS | PIERCE BIOTECHNOLOGY, INC. (US) | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180127822-A1 | MODIFIED NUCLEOTIDES METHODS AND KITS | RNGTT, NUDT1, ADAR | FGF1 4878/4885FGF2 4862/4885VEGFA 3706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.