SCHEMBL20131079

SCHEMBL20131079

Cc1cc(C)cc(CCN2CC=CC2=O)c1

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.35
CCR6 P51684 1/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
GAA P10253 1/20 0.33
DAO P14920 1/20 0.33
IDH1 O75874 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
NPSR1 Q6W5P4 2/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
RECQL P46063 1/20 0.32
RAB9A P51151 1/20 0.32
HRH3 Q9Y5N1 2/20 0.32
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4663313 0.76 GSK3A (0.55) GAADAOALDH1A1LMNAMAPT
SCHEMBL6481556 0.72
SCHEMBL8536193 0.69
SCHEMBL6779927 0.68 MGLL (0.50) HSP90AA1GAAALDH1A1MAPTHTT
SCHEMBL179104 0.68
SCHEMBL24300568 0.67 MGLL (0.48) HSP90AA1SMN1; SMN2NPSR1ALDH1A1LMNA
SCHEMBL2905468 0.67 MGLL (0.53) HSP90AA1SMN1; SMN2NPSR1ALDH1A1LMNA
SCHEMBL23132249 0.67 ALDH1A1 (0.32) CA1CA2ALDH1A1
SCHEMBL19014599 0.67 MGLL (0.47) HSP90AA1CCR6CA1CA2SMN1; SMN2
SCHEMBL8352726 0.66 CA1 (0.40) CA1CA2MAPTRAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180127498-A1 ANTI-FCRN ANTIBODIES UCB BIOPHARMA SPRL (BE) 2018-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180127498-A1 ANTI-FCRN ANTIBODIES FCGRT, FCGR1A, FCGR2A HSP90AA1 3408/4885CCR6 2226/4885CA1 4879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.