SCHEMBL2013224

SCHEMBL2013224

CC(C)=[Ti](F)Oc1cccc(C(C)(C)C)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
ACHE P22303 3/20 0.39
HDAC4 P56524 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
SOD1 P00441 1/20 0.38
LMNA P02545 1/20 0.38
POLB P06746 1/20 0.38
HTT P42858 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
RAF1 P04049 1/20 0.37
P2RY1 P47900 2/20 0.36
FFAR1 O14842 1/20 0.34
CETP P11597 1/20 0.34
KIF11 P52732 1/20 0.34
RXRA P19793 1/20 0.34
RXRB P28702 1/20 0.34
NPC1 O15118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL722226 0.98 CYP3A4 (0.42) CYP3A4CYP2C9CYP2C19ACHEHDAC4
Hydrochloric Acid SCHEMBL3803731 0.81 SOD1 (0.38) CYP3A4CYP2C9CYP2C19ACHEHDAC4
Hydrochloric Acid SCHEMBL724813 0.80 ACHE (0.41) CYP3A4CYP2C9CYP2C19ACHEHDAC4
SCHEMBL4564515 0.79 CYP3A4 (0.42) CYP3A4CYP2C9CYP2C19ACHEHDAC4
Hydrochloric Acid SCHEMBL723640 0.78 CYP3A4 (0.41) CYP3A4CYP2C9CYP2C19ACHEHDAC4
SCHEMBL3862769 0.78 RXRA (0.34) POLBRXRARXRBALDH1A1
Hydrochloric Acid SCHEMBL722139 0.77 RXRA (0.33) POLBRXRARXRB
Hydrochloric Acid SCHEMBL719894 0.77 CA1 (0.38) LMNAHTTNPC1ALDH1A1MAPT
SCHEMBL18118971 0.76 CYP3A4 (0.59) CYP3A4CYP2C9CYP2C19ACHEHDAC4
Hydrochloric Acid SCHEMBL2053794 0.75 CYP3A4 (0.39) CYP3A4CYP2C9CYP2C19ACHEHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011074688-A1 PRODUCTION PROCESS OF OLEFIN POLYMERIZATION CATALYST AND OLEFIN POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-23 WO disclosed