Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDNF | P23560 | 3/20 | 0.51 |
| ▸ | PTN | P21246 | 2/20 | 0.51 |
| ▸ | MDK | P21741 | 2/20 | 0.51 |
| ▸ | FGF1 | P05230 | 4/20 | 0.41 |
| ▸ | FGF2 | P09038 | 3/20 | 0.41 |
| ▸ | CXCL12 | P48061 | 3/20 | 0.39 |
| ▸ | VEGFA | P15692 | 3/20 | 0.39 |
| ▸ | BMP2 | P12643 | 2/20 | 0.39 |
| ▸ | SHH | Q15465 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CCL2 | P13500 | 2/20 | 0.36 |
| ▸ | CXCL10 | P02778 | 1/20 | 0.36 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.36 |
| ▸ | CCL5 | P13501 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30728023 | 0.87 | FGF1 (0.49) | BDNFPTNMDKFGF1FGF2 | |
| SCHEMBL20133080 | 0.84 | MAPK1 (0.51) | BDNFPTNMDKCXCL12VEGFA | |
| SCHEMBL18159115 | 0.80 | BDNF (0.59) | BDNFPTNMDKFGF1FGF2 | |
| SCHEMBL4957225 | 0.75 | CXCL10 (0.43) | BDNFPTNMDKFGF1FGF2 | |
| SCHEMBL2466010 | 0.75 | CXCL10 (0.43) | BDNFPTNMDKFGF1FGF2 | |
| SCHEMBL29535179 | 0.74 | BDNF (0.45) | BDNFPTNMDKFGF1FGF2 | |
| SCHEMBL29535178 | 0.74 | BDNF (0.45) | BDNFPTNMDKFGF1FGF2 | |
| SCHEMBL17287183 | 0.74 | CYP3A4 (0.61) | CYP3A4MAPTCYP2C9CYP2C19POLB | |
| SCHEMBL10897393 | 0.74 | CYP3A4 (0.61) | CYP3A4MAPTCYP2C9CYP2C19POLB | |
| SCHEMBL10897931 | 0.74 | CYP3A4 (0.61) | CYP3A4MAPTCYP2C9CYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210015888-A1 | SUPRAMOLECULAR GLYCOSAMINOGLYCANS | NORTHWESTERN UNIVERSITY | 2021-01-21 | — | — | US | disclosed |
| US-10792327-B2 | Supramolecular gylcosaminoglycans | NORTHWESTERN UNIVERSITY (US) | 2020-10-06 | — | — | US | disclosed |
| US-20180125924-A1 | SUPRAMOLECULAR GLYCOSAMINOGLYCANS | NORTHWESTERN UNIVERSITY | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210015888-A1 | SUPRAMOLECULAR GLYCOSAMINOGLYCANS | HPSE, CD44, GHITM | BDNF 2020/4885PTN 386/4885MDK 1000/4885 |
| US-20180125924-A1 | SUPRAMOLECULAR GLYCOSAMINOGLYCANS | HPSE, CD44, GHITM | BDNF 2020/4885PTN 386/4885MDK 1000/4885 |
| US-10792327-B2 | Supramolecular gylcosaminoglycans | HPSE, CD44, GYPA | BDNF 2325/4885PTN 743/4885MDK 1433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.