Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | BDNF | P23560 | 3/20 | 0.47 |
| ▸ | PTN | P21246 | 2/20 | 0.47 |
| ▸ | MDK | P21741 | 2/20 | 0.47 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.41 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.41 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.41 |
| ▸ | IGF2R | P11717 | 2/20 | 0.41 |
| ▸ | B4GALT1 | P15291 | 1/20 | 0.40 |
| ▸ | BMP2 | P12643 | 1/20 | 0.40 |
| ▸ | VEGFA | P15692 | 1/20 | 0.40 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18159076 | 0.84 | BDNF (0.58) | MAPK1BDNFPTNMDKHPSE | |
| SCHEMBL20132940 | 0.84 | BDNF (0.51) | MAPK1BDNFPTNMDKHPSE | |
| SCHEMBL17002053 | 0.84 | CA2 (0.47) | MAPK1BDNFPTNMDKHPSE | |
| SCHEMBL13702251 | 0.83 | MAPK1 (0.71) | MAPK1CA1CA2CA9ALDH1A1 | |
| SCHEMBL21018974 | 0.83 | MAPK1 (0.71) | MAPK1CA1CA2CA9ALDH1A1 | |
| SCHEMBL19903782 | 0.83 | MAPK1 (0.71) | MAPK1CA1CA2CA9ALDH1A1 | |
| SCHEMBL21940522 | 0.83 | MAPK1 (0.71) | MAPK1CA1CA2CA9ALDH1A1 | |
| SCHEMBL22576748 | 0.83 | MAPK1 (0.71) | MAPK1CA1CA2CA9ALDH1A1 | |
| SCHEMBL4290431 | 0.83 | MAPK1 (0.71) | MAPK1CA1CA2CA9ALDH1A1 | |
| SCHEMBL3717192 | 0.83 | MAPK1 (0.71) | MAPK1CA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210015888-A1 | SUPRAMOLECULAR GLYCOSAMINOGLYCANS | NORTHWESTERN UNIVERSITY | 2021-01-21 | — | — | US | disclosed |
| US-10792327-B2 | Supramolecular gylcosaminoglycans | NORTHWESTERN UNIVERSITY (US) | 2020-10-06 | — | — | US | disclosed |
| US-20180125924-A1 | SUPRAMOLECULAR GLYCOSAMINOGLYCANS | NORTHWESTERN UNIVERSITY | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210015888-A1 | SUPRAMOLECULAR GLYCOSAMINOGLYCANS | HPSE, CD44, GHITM | MAPK1 2077/4885BDNF 2020/4885PTN 386/4885 |
| US-20180125924-A1 | SUPRAMOLECULAR GLYCOSAMINOGLYCANS | HPSE, CD44, GHITM | MAPK1 2077/4885BDNF 2020/4885PTN 386/4885 |
| US-10792327-B2 | Supramolecular gylcosaminoglycans | HPSE, CD44, GYPA | MAPK1 2919/4885BDNF 2325/4885PTN 743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.