SCHEMBL20133374

SCHEMBL20133374

Cc1ccc(Oc2ccc(C)c(-c3cc(C)ccc3C)c2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TEAD4 Q15561 1/20 0.48
ALDH1A1 P00352 4/20 0.47
TDP1 Q9NUW8 3/20 0.47
MAPT P10636 2/20 0.47
POLB P06746 1/20 0.47
L3MBTL1 Q9Y468 3/20 0.46
HTT P42858 2/20 0.46
LPAR1 Q92633 1/20 0.44
LPAR3 Q9UBY5 1/20 0.44
AR P10275 2/20 0.42
KMT2A Q03164 4/20 0.42
MEN1 O00255 3/20 0.42
SMN1; SMN2 Q16637 3/20 0.41
ACHE P22303 1/20 0.39
PDE4A P27815 1/20 0.39
PDE4B Q07343 1/20 0.39
PDE4C Q08493 1/20 0.39
PDE4D Q08499 1/20 0.39
MMP13 P45452 1/20 0.39
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23785452 0.82 FFAR1 (0.42) TEAD4ALDH1A1TDP1MAPTPOLB
SCHEMBL19541796 0.82 LPAR1 (0.41) TEAD4ALDH1A1TDP1MAPTPOLB
SCHEMBL1723322 0.81 ACHE (0.52) ALDH1A1TDP1MAPTKMT2AMEN1
SCHEMBL10984775 0.80 KMT2A (0.55) TEAD4ALDH1A1TDP1MAPTPOLB
SCHEMBL10990207 0.80 KMT2A (0.55) TEAD4ALDH1A1TDP1MAPTPOLB
SCHEMBL257610 0.80 KMT2A (0.55) TEAD4ALDH1A1TDP1MAPTPOLB
SCHEMBL197716 0.79 ALDH1A1 (0.52) ALDH1A1TDP1MAPTKMT2AMEN1
SCHEMBL18483015 0.78 ALKBH3 (0.35) TEAD4ALDH1A1TDP1MAPTPOLB
SCHEMBL12629301 0.77 GSTP1 (0.55) ALDH1A1TDP1L3MBTL1HTTKMT2A
SCHEMBL20367017 0.77 KMT2A (0.41) TEAD4ALDH1A1TDP1MAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230149015-A1 SMALL DIAMETER FIBER BRAID WITH CENTRAL CORE MEMBER KURARAY CO., LTD. (JP) 2023-05-18 US disclosed
US-20220167976-A1 SMALL DIAMETER FIBER BRAID WITH CENTRAL CORE MEMBER KURARAY CO., LTD. (JP) 2022-06-02 US disclosed
US-10450415-B2 Polyamide compound, and method for producing same TOYOTA BOSHOKU KABUSHIKI KAISHA (JP) 2019-10-22 US disclosed
US-9994709-B2 Thermoplastic compositions having low smoke, methods of their manufacture, and uses thereof SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2018-06-12 US disclosed
US-20180127544-A1 POLYAMIDE COMPOUND, AND METHOD FOR PRODUCING SAME TOYOTA BOSHOKU KABUSHIKI KAISHA (JP) 2018-05-10 US disclosed