SCHEMBL257610

SCHEMBL257610

Cc1ccc(Oc2ccc(C)c(C)c2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.55
L3MBTL1 Q9Y468 3/20 0.55
LMNA P02545 1/20 0.55
GFER P55789 1/20 0.55
TEAD4 Q15561 1/20 0.54
MAPT P10636 3/20 0.53
SMN1; SMN2 Q16637 3/20 0.53
MEN1 O00255 2/20 0.53
HPGD P15428 2/20 0.53
TDP1 Q9NUW8 4/20 0.52
ALDH1A1 P00352 3/20 0.52
POLB P06746 1/20 0.52
NPC1 O15118 1/20 0.49
HAO1 Q9UJM8 1/20 0.47
AR P10275 2/20 0.46
HTT P42858 2/20 0.46
ACHE P22303 1/20 0.44
HTR2A P28223 1/20 0.43
SLC6A4 P31645 1/20 0.43
MMP13 P45452 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10984775 1.00 KMT2A (0.55) KMT2AL3MBTL1LMNAGFERTEAD4
SCHEMBL10990207 1.00 KMT2A (0.55) KMT2AL3MBTL1LMNAGFERTEAD4
SCHEMBL10993100 0.93 KMT2A (0.60) KMT2AL3MBTL1LMNAGFERTEAD4
SCHEMBL47864 0.93 KMT2A (0.60) KMT2AL3MBTL1LMNAGFERTEAD4
SCHEMBL47874 0.90 KMT2A (0.57) KMT2AL3MBTL1LMNAGFERMAPT
SCHEMBL12792078 0.87 KMT2A (0.45) KMT2AL3MBTL1LMNAGFERTEAD4
SCHEMBL11947076 0.86 ALDH1A1 (0.63) KMT2AL3MBTL1LMNAGFERTEAD4
SCHEMBL10259158 0.86 SMN1; SMN2 (0.62) KMT2AL3MBTL1LMNAGFERTEAD4
SCHEMBL16621786 0.85 HTT (0.69) KMT2AL3MBTL1LMNAGFERMAPT
SCHEMBL20871928 0.85 MAPT (0.49) KMT2AL3MBTL1LMNAGFERTEAD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4526984-A Autoxidation of alkyl-substituted aromatic ethers THE UPJOHN COMPANY (US) 1985-07-02 US claimed
US-11530357-B2 Liquid crystal alignment agent and liquid crystal panel SHARP KABUSHIKI KAISHA (JP) 2022-12-20 US disclosed
US-11384169-B2 Sealant composition, liquid crystal cell, and method of producing liquid crystal cell SHARP KABUSHIKI KAISHA (JP) 2022-07-12 US disclosed
US-11319514-B2 Composition for forming a coating film for removing foreign matters NISSAN CHEMICAL CORPORATION (JP) 2022-05-03 US disclosed
US-11201411-B2 Liquid crystal cell and scanning antenna SHARP KABUSHIKI KAISHA (JP) 2021-12-14 US disclosed
US-11201403-B2 Liquid crystal cell and scanning antenna SHARP KABUSHIKI KAISHA (JP) 2021-12-14 US disclosed
US-11189914-B2 Liquid crystal cell and scanning antenna SHARP KABUSHIKI KAISHA (JP) 2021-11-30 US disclosed
US-11078324-B2 Seal material composition, liquid crystal cell, and scanned antenna SHARP KABUSHIKI KAISHA (JP) 2021-08-03 US disclosed
US-11079634-B2 Liquid crystal display device and method for manufacturing same SHARP KABUSHIKI KAISHA (JP) 2021-08-03 US disclosed
WO-2021131501-A1 POLYIMIDE RESIN COMPOSITION AND MOLDED BODY 三菱瓦斯化学株式会社 2021-07-01 WO disclosed
US-20070244120-A1 INHIBITION OF RAF KINASE USING SUBSTITUTED HETEROCYCLIC UREAS BAYER HEALTHCARE LLC 2007-10-18 US disclosed
US-20070244120-A1 INHIBITION OF RAF KINASE USING SUBSTITUTED HETEROCYCLIC UREAS BAYER HEALTHCARE LLC 2007-10-18 US disclosed
US-20070004228-A1 Polyamide acid-containing composition for forming antireflective film NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2007-01-04 US disclosed
US-20050054882-A1 Diaryl ether condensation reactions NSF - DEITR 2005-03-10 US disclosed
US-6762329-B2 EFFECTS OF ACIDIC ACTIVATORS ON ULLMANN-TYPE COUPLINGS INVOLVING ELECTRON-POOR AND/OR RELATIVELY INSOLUBLE SUBSTRATES. MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2004-07-13 US disclosed
US-20030088128-A1 Diaryl ether condensation reactions NATIONAL SCIENCE FOUNDATION 2003-05-08 US disclosed
WO-2003007954-A2 SULFONYL ARYL HYDROXAMATES AND THEIR USE AS MATRIX METALLOPROTEASE INHIBITORS PHARMACIA CORPORATION (US) 2003-01-30 WO disclosed
US-6395939-B1 CATALYTIC ETHERIFICATION AND CONDENSATION WITH COPPER CATALYSTS MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2002-05-28 US disclosed
WO-1999018057-A1 PREPARATION OF DIARYL ETHER BY CONDENSATION REACTIONS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1999-04-15 WO disclosed
US-4526984-A Autoxidation of alkyl-substituted aromatic ethers THE UPJOHN COMPANY (US) 1985-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050054882-A1 Diaryl ether condensation reactions NSFL1C, DERL1, UBE2M KMT2A 1576/4885L3MBTL1 3571/4885LMNA 1722/4885
US-20030088128-A1 Diaryl ether condensation reactions NSFL1C, DERL1, UBE2M KMT2A 1576/4885L3MBTL1 3571/4885LMNA 1722/4885
US-20070244120-A1 INHIBITION OF RAF KINASE USING SUBSTITUTED HETEROCYCLIC UREAS BRAF, RAF1, ARAF KMT2A 1462/4885L3MBTL1 1879/4885LMNA 3637/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.