Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 12/20 | 0.34 |
| ▸ | NPY1R | P25929 | 9/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.34 |
| ▸ | NPY2R | P49146 | 5/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22807623 | 0.84 | CNR1 (0.33) | CNR1ITGB3ITGA2B | |
| SCHEMBL21782662 | 0.80 | DPP7 (0.41) | NPY4RNPY1RNPY5RNPY2RALOX15 | |
| SCHEMBL21782696 | 0.79 | GNAI3 (0.41) | NPY4RNPY1RNPY5RNPY2RALOX15 | |
| SCHEMBL27354286 | 0.79 | ALOX15 (0.37) | NPY4RNPY1RNPY5RNPY2RALOX15 | |
| SCHEMBL4798412 | 0.77 | DPP7 (0.47) | NPY4RNPY1RNPY5RNPY2RALOX15 | |
| SCHEMBL4798434 | 0.77 | DPP7 (0.47) | NPY4RNPY1RNPY5RNPY2RALOX15 | |
| SCHEMBL21782715 | 0.77 | DPP7 (0.39) | NPY4RNPY1RNPY5RNPY2RALOX15 | |
| SCHEMBL20169777 | 0.77 | DPP7 (0.51) | CNR1 | |
| SCHEMBL8297085 | 0.76 | ALOX15 (0.40) | NPY4RNPY1RNPY5RNPY2RALOX15 | |
| SCHEMBL13402408 | 0.76 | ALOX15 (0.40) | NPY4RNPY1RNPY5RNPY2RALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180126013-A1 | RADIOTHERAPEUTIC AND COMPANION IMAGING AGENTS TO TARGET MC1R | WAKE FOREST UNIVERSITY | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180126013-A1 | RADIOTHERAPEUTIC AND COMPANION IMAGING AGENTS TO TARGET MC1R | MC1R, MC3R, MC5R | NPY4R 143/4885NPY1R 24/4885NPY5R 79/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.