Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KCNQ3 | O43525 | 3/20 | 0.45 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.45 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.45 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20133974 | 0.83 | KCNQ2 (0.65) | ALDH1A1KCNQ3KCNQ2KCNQ4KCNQ5 | |
| SCHEMBL2235641 | 0.81 | KCNQ2 (0.70) | ALDH1A1KCNQ3KCNQ2KCNQ4KCNQ5 | |
| SCHEMBL6005439 | 0.78 | KCNQ2 (0.64) | ALDH1A1KCNQ3KCNQ2KCNQ4KCNQ5 | |
| SCHEMBL8966006 | 0.76 | KCNQ2 (0.58) | ALDH1A1KCNQ3KCNQ2KCNQ4KCNQ5 | |
| SCHEMBL15538708 | 0.76 | MAPT (0.52) | ALDH1A1KCNQ3KCNQ2KCNQ4KCNQ5 | |
| SCHEMBL6004947 | 0.75 | CYP1A2 (0.65) | ALDH1A1KMT2AMAPTCYP1A2CYP2C9 | |
| SCHEMBL6004798 | 0.74 | KCNQ2 (0.56) | ALDH1A1KCNQ3KCNQ2KCNQ4KCNQ5 | |
| SCHEMBL14230958 | 0.74 | ALDH1A1 (0.59) | ALDH1A1KMT2AMAPTCYP1A2CYP2C9 | |
| SCHEMBL20133978 | 0.73 | FFAR4 (0.43) | ALDH1A1KMT2AMAPTMEN1LMNA | |
| SCHEMBL6448712 | 0.73 | KCNQ2 (0.50) | ALDH1A1KCNQ3KCNQ2KCNQ4KCNQ5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180127357-A1 | (2-AMINO-4-(ARYLAMINO)PHENYL) CARBAMATES | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180127357-A1 | (2-AMINO-4-(ARYLAMINO)PHENYL) CARBAMATES | HRH4, H1-10, HDAC10 | ALDH1A1 2275/4885KCNQ3 1235/4885KCNQ2 1257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.