Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HRAS | P01112 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2236853 | 0.74 | HTT (0.49) | ALDH1A1MAPTTDP1MEN1KMT2A | |
| SCHEMBL20133957 | 0.73 | ALDH1A1 (0.49) | ALDH1A1MAPTTDP1MEN1KMT2A | |
| SCHEMBL537892 | 0.73 | TDP1 (0.64) | FFAR4ALDH1A1MAPTTDP1MEN1 | |
| Fluoride SCHEMBL27394412 | 0.71 | TDP1 (0.62) | FFAR4ALDH1A1MAPTTDP1MEN1 | |
| SCHEMBL720358 | 0.70 | TDP1 (0.79) | ALDH1A1MAPTTDP1MEN1KMT2A | |
| SCHEMBL30515345 | 0.69 | ALDH1A1 (0.64) | ALDH1A1MAPTTDP1MEN1KMT2A | |
| SCHEMBL204956 | 0.69 | ALDH1A1 (0.64) | ALDH1A1MAPTTDP1MEN1KMT2A | |
| SCHEMBL112673 | 0.69 | TSHR (0.59) | FFAR4ALDH1A1MAPTTDP1MEN1 | |
| Carbamic Acid SCHEMBL28266550 | 0.69 | LMNA (0.51) | FFAR4ALDH1A1MAPTTDP1MEN1 | |
| SCHEMBL8966735 | 0.68 | FFAR1 (0.47) | FFAR4ALDH1A1MAPTTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180127357-A1 | (2-AMINO-4-(ARYLAMINO)PHENYL) CARBAMATES | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180127357-A1 | (2-AMINO-4-(ARYLAMINO)PHENYL) CARBAMATES | HRH4, H1-10, HDAC10 | FFAR4 327/4885ALDH1A1 2275/4885MAPT 4337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.