Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7963768 | 0.78 | GSR (0.35) | ALDH1A1KDM4E | |
| SCHEMBL11020293 | 0.77 | TSHR (0.38) | ALDH1A1ALOX15MEN1CYP3A4KMT2A | |
| SCHEMBL19841951 | 0.77 | LMNA (0.39) | ALDH1A1KDM4ELMNAALOX15TP53 | |
| SCHEMBL22891226 | 0.76 | LMNA (0.37) | ALDH1A1LMNAALOX15MEN1CYP3A4 | |
| SCHEMBL13912971 | 0.76 | TDP1 (0.38) | ALDH1A1KDM4ELMNAALOX15TP53 | |
| Hydrochloric Acid SCHEMBL6893639 | 0.75 | GSR (0.37) | ALDH1A1KDM4E | |
| SCHEMBL19841913 | 0.75 | PAOX (0.37) | ALDH1A1LMNAALOX15TP53MEN1 | |
| SCHEMBL23080315 | 0.75 | ALDH1A1 (0.36) | ALDH1A1KDM4ELMNAALOX15TP53 | |
| SCHEMBL6119034 | 0.74 | ALDH1A1 (0.40) | ALDH1A1LMNAMEN1CYP3A4KMT2A | |
| SCHEMBL11501644 | 0.74 | LMNA (0.52) | ALDH1A1LMNAALOX15MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180125826-A1 | SUBSTITUTED 1H-IMIDAZO[4,5-b]PYRIDIN-2(3H)-ONES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (JP) | 2018-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180125826-A1 | SUBSTITUTED 1H-IMIDAZO[4,5-b]PYRIDIN-2(3H)-ONES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | GRIN2B, GRIN2A, GRIN2C | ALDH1A1 1382/4885KDM4E 2545/4885LMNA 2730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.