Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | CTSG | P08311 | 1/20 | 0.30 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.30 |
| ▸ | CMA1 | P23946 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17314985 | 0.82 | ACE2 (0.42) | TSHRALDH1A1ACE2MEN1CYP3A4 | |
| SCHEMBL11922983 | 0.81 | TSHR (0.41) | TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL23869885 | 0.80 | TSHR (0.50) | TSHRALDH1A1ACE2S1PR2S1PR4 | |
| SCHEMBL19749942 | 0.80 | TSHR (0.52) | TSHRALDH1A1MEN1KMT2ACA1 | |
| SCHEMBL4317793 | 0.80 | TSHR (0.46) | TSHRALDH1A1ACE2MEN1CYP3A4 | |
| SCHEMBL4612569 | 0.79 | ALDH1A1 (0.42) | TSHRALDH1A1ACE2MEN1ALOX15 | |
| SCHEMBL1426138 | 0.78 | TSHR (0.46) | TSHRACE2MEN1CYP3A4ALOX15 | |
| SCHEMBL17831473 | 0.78 | TSHR (0.50) | TSHRALDH1A1MEN1KMT2ACA1 | |
| SCHEMBL20134288 | 0.77 | ALDH1A1 (0.33) | ALDH1A1MEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL1552856 | 0.77 | TSHR (0.41) | TSHRALDH1A1MEN1ALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0159582-A1 | Process for preparing polyphenylene ethers | BASF Aktiengesellschaft (DE) | 1985-10-30 | — | — | EP | disclosed |