SCHEMBL20134677

SCHEMBL20134677

CCCCO[SiH](C)CCCC

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.38
ADRB1 P08588 1/20 0.38
ADRB3 P13945 1/20 0.38
TSHR P16473 2/20 0.33
CYP3A4 P08684 1/20 0.33
ALDH1A1 P00352 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
LMNA P02545 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3482206 0.90 ADRB2 (0.32) ADRB2ADRB1ADRB3TSHRLMNA
SCHEMBL2772988 0.90 ADRB2 (0.38) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL27904647 0.86 TSHR (0.42) ADRB2ADRB1ADRB3TSHRALDH1A1
SCHEMBL28457404 0.86
SCHEMBL8953945 0.86 DNM1 (0.39) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL28449536 0.84 TSHR (0.32) TSHRALDH1A1
SCHEMBL17209123 0.84 THRB (0.35) TSHRCA1CA2
SCHEMBL12627227 0.83 CYP3A4 (0.30) CYP3A4
SCHEMBL28956702 0.82 CA1 (0.33) TSHRCA1CA2
SCHEMBL2770121 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10995249-B2 Tire with reduced cavity noise HANKOOK TIRE CO., LTD. 2021-05-04 US disclosed
US-10947430-B2 Tire with reduced cavity noise HANKOOK TIRE CO., LTD. 2021-03-16 US disclosed
EP-3321108-B1 TIRE WITH REDUCED CAVITY NOISE HANKOOK TIRE CO LTD (KR) 2019-05-15 EP disclosed
CN-108688415-A Cavity Noise reduction tire 韩国轮胎株式会社 2018-10-23 CN disclosed
US-20180282600-A1 TIRE WITH REDUCED CAVITY NOISE HANKOOK TIRE CO., LTD. (KR) 2018-10-04 US disclosed
EP-3381712-A1 TIRE WITH REDUCED CAVITY NOISE Hankook Tire Co., Ltd. (KR) 2018-10-03 EP disclosed
US-20180134933-A1 TIRE WITH REDUCED CAVITY NOISE HANKOOK TIRE CO., LTD. (KR) 2018-05-17 US disclosed
EP-3321108-A1 TIRE WITH REDUCED CAVITY NOISE Hankook Tire Co., Ltd. (KR) 2018-05-16 EP disclosed