Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Isopropylbenzene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isopropylbenzene SCHEMBL719551 | 0.95 | CNR2 (0.42) | CNR2PTPN1PTPN6PTPN11ALDH1A1 | |
| Isopropylbenzene SCHEMBL7897749 | 0.93 | ALDH1A1 (0.44) | CNR2PTPN1PTPN6PTPN11ALDH1A1 | |
| Isopropylbenzene SCHEMBL8554353 | 0.91 | ALDH1A1 (0.43) | CNR2PTPN1PTPN6PTPN11ALDH1A1 | |
| Isopropylbenzene SCHEMBL7897754 | 0.85 | LMNA (0.46) | CNR2PTPN1PTPN6PTPN11ALDH1A1 | |
| Isopropylbenzene SCHEMBL3531285 | 0.83 | PTPN1 (0.42) | CNR2PTPN1PTPN6PTPN11ALDH1A1 | |
| Isopropylbenzene SCHEMBL894807 | 0.83 | ALDH1A1 (0.57) | PTPN1PTPN6PTPN11ALDH1A1MAPT | |
| Isopropylbenzene SCHEMBL27353084 | 0.83 | ALDH1A1 (0.57) | PTPN1PTPN6PTPN11ALDH1A1MAPT | |
| Isopropylbenzene SCHEMBL1416132 | 0.83 | ALDH1A1 (0.44) | CNR2PTPN1PTPN6PTPN11ALDH1A1 | |
| Isopropylbenzene SCHEMBL8555471 | 0.82 | ALDH1A1 (0.52) | CNR2PTPN1PTPN6PTPN11ALDH1A1 | |
| Isopropylbenzene SCHEMBL11254813 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026106745-A1 | LATEX COMPOSITION WITH NON-BIOCIDAL PRESERVATIVE | ROHM AND HAAS COMPANY (US) | 2026-05-21 | — | — | WO | claimed |
| EP-2504376-B1 | POLYOL ACRYLATES FOR USE IN ENERGY CURABLE INKS | STEPAN CO (US) | 2018-03-21 | — | — | EP | disclosed |
| EP-2804887-B1 | POLYESTER POLYOLS CONTAINING DIELS-ALDER OR ENE ADDUCTS | STEPAN CO (US) | 2017-03-01 | — | — | EP | disclosed |
| US-9447225-B2 | Polyester polyols containing diels-alder or ene adducts | STEPAN COMPANY (US) | 2016-09-20 | — | — | US | disclosed |
| US-9394401-B2 | Polyol acrylates for use in energy curable inks | STEPAN COMPANY (US) | 2016-07-19 | — | — | US | disclosed |
| US-20140378570-A1 | Polyester Polyols Containing Diels-Alder or Ene Adducts | STEPAN COMPANY | 2014-12-25 | — | — | US | disclosed |
| EP-2804887-A1 | POLYESTER POLYOLS CONTAINING DIELS-ALDER OR ENE ADDUCTS | Stepan Company (US) | 2014-11-26 | — | — | EP | disclosed |
| WO-2013109834-A1 | POLYESTER POLYOLS CONTAINING DIELS-ALDER OR ENE ADDUCTS | STEPAN COMPANY (US) | 2013-07-25 | — | — | WO | disclosed |
| EP-2504376-A1 | POLYOL ACRYLATES FOR USE IN ENERGY CURABLE INKS | Stepan Company (US) | 2012-10-03 | — | — | EP | disclosed |
| US-20120245246-A1 | Polyol Acrylates for Use in Energy Curable Inks | STEPAN COMPANY | 2012-09-27 | — | — | US | disclosed |
| WO-2011066313-A1 | POLYOL ACRYLATES FOR USE IN ENERGY CURABLE INKS | STEPAN CORPORATION (US) | 2011-06-03 | — | — | WO | disclosed |