Isopropylbenzene

Isopropylbenzene

SCHEMBL7897754

CC(C)c1ccccc1.O=S(=O)([O-])O.[Fe+2].[O-]O

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

CYP51cyp51Acyp51c

The experimentally established mechanism targets of Isopropylbenzene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.46
ALDH1A1 P00352 3/20 0.46
MAPT P10636 3/20 0.46
KMT2A Q03164 2/20 0.46
KDM4E B2RXH2 2/20 0.46
GMNN O75496 1/20 0.46
POLB P06746 1/20 0.46
HPGD P15428 1/20 0.46
PMP22 Q01453 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
PTPN1 P18031 1/20 0.45
PTPN6 P29350 1/20 0.45
PTPN11 Q06124 1/20 0.45
SRC P12931 1/20 0.44
CNR2 P34972 2/20 0.40
CRHBP P24387 1/20 0.39
CRHR2 Q13324 1/20 0.39
KAT6A Q92794 2/20 0.39
MEN1 O00255 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isopropylbenzene SCHEMBL7897749 0.91 ALDH1A1 (0.44) LMNAALDH1A1MAPTKMT2AKDM4E
Isopropylbenzene SCHEMBL8555471 0.89 ALDH1A1 (0.52) LMNAALDH1A1MAPTKMT2AKDM4E
Isopropylbenzene SCHEMBL8554353 0.89 ALDH1A1 (0.43) LMNAALDH1A1MAPTKMT2AKDM4E
Isopropylbenzene SCHEMBL894807 0.87 ALDH1A1 (0.57) LMNAALDH1A1MAPTKMT2AKDM4E
Isopropylbenzene SCHEMBL27353084 0.87 ALDH1A1 (0.57) LMNAALDH1A1MAPTKMT2AKDM4E
Isopropylbenzene SCHEMBL3423779 0.87 ADRA2C (0.46) LMNAALDH1A1KMT2AKDM4ECRHBP
Isopropylbenzene SCHEMBL2013494 0.85 CNR2 (0.42) LMNAALDH1A1MAPTKMT2AKDM4E
Isopropylbenzene SCHEMBL719551 0.85 CNR2 (0.42) LMNAALDH1A1MAPTKMT2AKDM4E
Isopropylbenzene SCHEMBL2013493 0.85 ALDH1A1 (0.55) LMNAALDH1A1MAPTKMT2AKDM4E
Isopropylbenzene SCHEMBL8330332 0.85 ALDH1A1 (0.55) LMNAALDH1A1MAPTKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6184281-B1 FOR PLASTIC CONTAINERS; DURING RECYCLING IONOMERIC COATINGS ARE REMOVABLE FROM PLASTIC CONTAINERS USING CAUSTIC TREATMENT THE GLIDDEN COMPANY 2001-02-06 US disclosed
US-5877239-A CROSSLINKED COATING THE GLIDDEN COMPANY (US) 1999-03-02 US disclosed
US-5733970-A CROSSLINKING WITH LOW MOLECULAR WEIGHT POLYEPOXIDE THE GLIDDEN COMPANY (US) 1998-03-31 US disclosed
EP-0114909-A1 Thermosetting acrylic polyvinylidene fluorine composition THE GLIDDEN COMPANY (US) 1984-08-08 EP disclosed
US-4226752-A LARGE SIZE PARTICLES, TWO-STEP PROCESS, SEEDING SCM CORPORATION (US) 1980-10-07 US disclosed