Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | UBE2M | P61081 | 1/20 | 0.38 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.38 |
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.37 |
| ▸ | ADAMTS7 | Q9UKP4 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20134970 | 1.00 | MGLL (0.39) | MGLLMEN1KMT2AEGLN1UBE2M | |
| SCHEMBL20135436 | 0.88 | ADAMTS5 (0.39) | MGLLMEN1KMT2AEGLN1UBE2M | |
| SCHEMBL20135434 | 0.88 | ADAMTS5 (0.39) | MGLLMEN1KMT2AEGLN1UBE2M | |
| SCHEMBL20134838 | 0.88 | ADAMTS5 (0.42) | MGLLMEN1KMT2AEGLN1UBE2M | |
| SCHEMBL20134839 | 0.88 | ADAMTS5 (0.42) | MGLLMEN1KMT2AEGLN1UBE2M | |
| SCHEMBL20135362 | 0.84 | UBE2M (0.39) | MGLLMEN1KMT2AUBE2MDCUN1D1 | |
| SCHEMBL20135363 | 0.84 | UBE2M (0.39) | MGLLMEN1KMT2AUBE2MDCUN1D1 | |
| SCHEMBL20134774 | 0.80 | UBE2M (0.39) | MGLLMEN1KMT2AEGLN1UBE2M | |
| SCHEMBL20134773 | 0.80 | UBE2M (0.39) | MGLLMEN1KMT2AEGLN1UBE2M | |
| SCHEMBL20134876 | 0.79 | MEN1 (0.65) | MGLLMEN1KMT2AALDH1A1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3321256-A1 | NOVEL IMIDE DERIVATIVES AND USE THEREOF AS MEDICINE | Mitsubishi Tanabe Pharma Corporation (JP) | 2018-05-16 | — | — | EP | disclosed |