Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC6 | Q9Y210 | 4/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.37 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.37 |
| ▸ | SMO | Q99835 | 3/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17248015 | 0.80 | NOS3 (0.45) | SSTR4CHRM4SMOPDE10A | |
| SCHEMBL18422308 | 0.77 | SSTR4 (0.43) | SSTR4 | |
| SCHEMBL15180524 | 0.77 | TP53 (0.48) | EPHX2 | |
| SCHEMBL12250792 | 0.77 | NOS3 (0.42) | CHRM4PROKR1PDE10A | |
| SCHEMBL21045800 | 0.77 | TRPC6 (0.54) | TRPC6EPHX2L3MBTL1 | |
| SCHEMBL21796728 | 0.75 | FASN (0.39) | CHRM4 | |
| SCHEMBL28008471 | 0.73 | L3MBTL1 (0.39) | TRPC6CHRM4TRPV1MAPK7L3MBTL1 | |
| SCHEMBL25386216 | 0.72 | OPRL1 (0.36) | TRPC6CHRM4MAPK7 | |
| SCHEMBL19520542 | 0.72 | NOS3 (0.41) | TRPC6SSTR4 | |
| SCHEMBL1939255 | 0.72 | TRPC6 (0.57) | TRPC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3321256-A1 | NOVEL IMIDE DERIVATIVES AND USE THEREOF AS MEDICINE | Mitsubishi Tanabe Pharma Corporation (JP) | 2018-05-16 | — | — | EP | disclosed |