Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 3/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.36 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMO | Q99835 | 1/20 | 0.35 |
| ▸ | OGA | O60502 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3557685 | 0.75 | KDM4E (0.52) | OPRK1ALDH1A1HPGD | |
| SCHEMBL27697487 | 0.74 | CHRM1 (0.43) | OPRK1CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL29688884 | 0.74 | EIF2AK4 (0.46) | — | |
| SCHEMBL20135256 | 0.74 | EIF2AK4 (0.46) | — | |
| SCHEMBL20135253 | 0.74 | EIF2AK4 (0.46) | — | |
| SCHEMBL29688824 | 0.73 | GPR119 (0.48) | CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL20134910 | 0.73 | GPR119 (0.48) | CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL20135523 | 0.73 | GPR119 (0.48) | CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL29688701 | 0.73 | GPR119 (0.48) | CHRM1CHRM2CHRM4CHRM3 | |
| SCHEMBL20134912 | 0.73 | GPR119 (0.48) | CHRM1CHRM2CHRM4CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3321256-A1 | NOVEL IMIDE DERIVATIVES AND USE THEREOF AS MEDICINE | Mitsubishi Tanabe Pharma Corporation (JP) | 2018-05-16 | — | — | EP | disclosed |