Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 7/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20135253 | 1.00 | EIF2AK4 (0.46) | EIF2AK4NR1H2NR1H3LMNANPSR1 | |
| SCHEMBL29688884 | 1.00 | EIF2AK4 (0.46) | EIF2AK4NR1H2NR1H3LMNANPSR1 | |
| SCHEMBL29688914 | 0.88 | NR1H2 (0.54) | EIF2AK4NR1H2NR1H3LMNANPSR1 | |
| SCHEMBL20791568 | 0.88 | NR1H2 (0.54) | EIF2AK4NR1H2NR1H3LMNANPSR1 | |
| SCHEMBL29688824 | 0.87 | GPR119 (0.48) | LMNAMAP4K4HDAC1MAPTGPR119 | |
| SCHEMBL20135523 | 0.87 | GPR119 (0.48) | LMNAMAP4K4HDAC1MAPTGPR119 | |
| SCHEMBL29688701 | 0.87 | GPR119 (0.48) | LMNAMAP4K4HDAC1MAPTGPR119 | |
| SCHEMBL20134912 | 0.87 | GPR119 (0.48) | LMNAMAP4K4HDAC1MAPTGPR119 | |
| SCHEMBL20134910 | 0.87 | GPR119 (0.48) | LMNAMAP4K4HDAC1MAPTGPR119 | |
| SCHEMBL29688643 | 0.85 | DPP4 (0.42) | NR1H2NR1H3LMNANPSR1MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10407408-B2 | Imide derivatives and use thereof as medicine | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2019-09-10 | — | — | US | disclosed |
| US-20190077787-A1 | NOVEL IMIDE DERIVATIVES AND USE THEREOF AS MEDICINE | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2019-03-14 | — | — | US | disclosed |
| EP-3321256-A1 | NOVEL IMIDE DERIVATIVES AND USE THEREOF AS MEDICINE | Mitsubishi Tanabe Pharma Corporation (JP) | 2018-05-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190077787-A1 | NOVEL IMIDE DERIVATIVES AND USE THEREOF AS MEDICINE | MMP9, MMP10, MMP1 | EIF2AK4 1250/4885NR1H2 3477/4885NR1H3 3904/4885 |
| US-10407408-B2 | Imide derivatives and use thereof as medicine | MMP9, MMP2, MMP1 | EIF2AK4 1098/4885NR1H2 3531/4885NR1H3 3916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.