Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.39 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 2/20 | 0.32 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2013604 | 0.79 | AR (0.40) | ARGCGRMEN1KMT2A | |
| SCHEMBL15621301 | 0.72 | AR (0.47) | ARDCLRE1BACLYGCGRMEN1 | |
| SCHEMBL14742437 | 0.71 | EPAS1 (0.32) | AR | |
| SCHEMBL2015782 | 0.69 | NT5E (0.36) | DCLRE1BMEN1KMT2ARELA | |
| SCHEMBL2018081 | 0.69 | FBP1 (0.39) | ARACLYMEN1KMT2A | |
| SCHEMBL2014653 | 0.68 | CSNK2A2 (0.39) | GCGRADORA1 | |
| SCHEMBL2013731 | 0.67 | AR (0.36) | ARADORA1MEN1KMT2A | |
| SCHEMBL9952150 | 0.67 | AR (0.36) | ARDCLRE1BACLYRELA | |
| SCHEMBL2019261 | 0.67 | PIK3CD (0.44) | ACLYGCGRADORA1KMT2A | |
| SCHEMBL2016569 | 0.64 | NT5E (0.36) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011075630-A1 | SUBSTITUTED FUSED ARYL AND HETEROARYL DERIVATIVES AS PI3K INHIBITORS | INCYTE CORPORATION (US) | 2011-06-23 | — | — | WO | disclosed |