Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29290647 | 0.81 | LMNA (0.47) | LMNAKMT2AMEN1TSHRTDP1 | |
| SCHEMBL93484 | 0.79 | LMNA (0.52) | LMNACA12CA1CA2CA3 | |
| SCHEMBL7063095 | 0.79 | LMNA (0.52) | LMNACA12CA1CA2CA3 | |
| SCHEMBL7492345 | 0.79 | LMNA (0.52) | LMNACA12CA1CA2CA3 | |
| SCHEMBL9333110 | 0.77 | LMNA (0.70) | LMNACA12CA1CA2CA3 | |
| SCHEMBL8067929 | 0.74 | LMNA (0.46) | LMNACA12CA1CA2CA3 | |
| SCHEMBL226372 | 0.73 | SMN1; SMN2 (0.45) | LMNACA12CA1CA2CA3 | |
| SCHEMBL225584 | 0.73 | SMN1; SMN2 (0.45) | LMNACA12CA1CA2CA3 | |
| SCHEMBL195052 | 0.72 | — | — | |
| SCHEMBL17377711 | 0.72 | LMNA (0.57) | LMNACA12CA1CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414456-B1 | DEGRADABLE POLYMER COMPOSITIONS AND USES THEREOF | ISP INVESTMENTS LLC (US) | 2018-12-26 | — | — | EP | claimed |
| EP-2346909-B1 | POLYMERS DERIVED FROM N-VINYL FORMAMIDE, VINYL AMIDES OR ACRYLAMIDES, AND REACTION SOLVENT, AND THE USES THEREOF | ISP INVESTMENTS INC (US) | 2018-05-16 | — | — | EP | claimed |