SCHEMBL20137318

SCHEMBL20137318

CC1(C)c2ccccc2-c2ccc(-c3cc(-c4cccc(-c5ccc(N(c6ccc(-c7ccccc7)cc6)c6ccc7c(c6)C(C)(C)c6ccccc6-7)cc5)c4)ncn3)cc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMO O15229 1/20 0.40
▸ PDK2 Q15119 14/20 0.37
▸ KMT2A Q03164 2/20 0.34
▸ CYP1A2 P05177 2/20 0.34
▸ CYP3A4 P08684 2/20 0.34
▸ KDM4E B2RXH2 1/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ ALDH1A1 P00352 1/20 0.34
▸ TP53 P04637 1/20 0.34
▸ MAPT P10636 1/20 0.34
▸ HPGD P15428 1/20 0.34
▸ MAPK1 P28482 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ HSD17B10 Q99714 1/20 0.34
▸ USP2 O75604 1/20 0.32
▸ CYP2D6 P10635 1/20 0.32
▸ CYP2C9 P11712 1/20 0.32
▸ TSHR P16473 1/20 0.32
▸ CYP2C19 P33261 1/20 0.32
▸ CLK4 Q9HAZ1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20149263 0.95 PDK2 (0.34) KMOPDK2KMT2ACYP1A2CYP3A4
SCHEMBL20137313 0.94 KMT2A (0.36) KMOPDK2KMT2ACYP1A2CYP3A4
SCHEMBL29450675 0.94 KMT2A (0.36) KMOPDK2KMT2ACYP1A2CYP3A4
SCHEMBL20137315 0.94 KMT2A (0.39) KMOPDK2KMT2ACYP1A2CYP3A4
SCHEMBL20149262 0.94 KMT2A (0.39) KMOPDK2KMT2ACYP1A2CYP3A4
SCHEMBL29450666 0.94 KMT2A (0.39) KMOPDK2KMT2ACYP1A2CYP3A4
SCHEMBL17153665 0.91 PDK2 (0.43) PDK2
SCHEMBL19797633 0.91 PDK2 (0.43) PDK2
SCHEMBL16366523 0.91 PDK2 (0.43) PDK2
SCHEMBL16366615 0.91 PDK2 (0.43) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114284447-A Organic compound, light-emitting element, and method for synthesizing organic compound 株式会社半导体能源研究所 2022-04-05 — — CN disclosed
CN-108075044-B Light-emitting element, display device, electronic device, and lighting device 株式会社半导体能源研究所 2022-01-25 — — CN disclosed
US-10749112-B2 Light-emitting element, display device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-08-18 — — US disclosed
US-10749112-B2 Light-emitting element, display device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-08-18 — — US disclosed
US-20190245146-A1 Light-Emitting Element, Display Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-08-08 — — US disclosed
US-20190245146-A1 Light-Emitting Element, Display Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-08-08 — — US disclosed
US-10270039-B2 Light-emitting element, display device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-04-23 — — US disclosed
US-10270039-B2 Light-emitting element, display device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-04-23 — — US disclosed
US-20180138416-A1 Light-Emitting Element, Display Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-05-17 — — US disclosed
US-20180138416-A1 Light-Emitting Element, Display Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-05-17 — — US disclosed
US-20180138416-A1 Light-Emitting Element, Display Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-05-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180138416-A1 Light-Emitting Element, Display Device, Electronic Device, and Lighting Device ESR1, EHD1, PPOX KMO 1042/4885PDK2 3250/4885KMT2A 2198/4885
US-10270039-B2 Light-emitting element, display device, electronic device, and lighting device ESR1, EHD1, PPOX KMO 1042/4885PDK2 3250/4885KMT2A 2198/4885
US-20190245146-A1 Light-Emitting Element, Display Device, Electronic Device, and Lighting Device ESR1, EHD1, PPOX KMO 1042/4885PDK2 3250/4885KMT2A 2198/4885
US-10749112-B2 Light-emitting element, display device, electronic device, and lighting device ESR1, EHD1, PPOX KMO 1042/4885PDK2 3250/4885KMT2A 2198/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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