SCHEMBL20149262

SCHEMBL20149262

CC1(C)c2ccccc2-c2ccc(N(c3ccc(-c4ccccc4)cc3)c3ccc(-c4cc(-c5ccc(N(c6ccc(-c7ccccc7)cc6)c6ccc7c(c6)C(C)(C)c6ccccc6-7)cc5)ncn4)cc3)cc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 3/20 0.39
▸ SMN1; SMN2 Q16637 3/20 0.39
▸ CYP1A2 P05177 3/20 0.39
▸ KDM4E B2RXH2 2/20 0.39
▸ MEN1 O00255 2/20 0.39
▸ ALDH1A1 P00352 2/20 0.39
▸ CYP3A4 P08684 2/20 0.39
▸ MAPT P10636 2/20 0.39
▸ HPGD P15428 2/20 0.39
▸ HSD17B10 Q99714 2/20 0.39
▸ TP53 P04637 1/20 0.39
▸ MAPK1 P28482 1/20 0.39
▸ PDK2 Q15119 5/20 0.36
▸ MIF P14174 1/20 0.36
▸ ASIC3 Q9UHC3 1/20 0.36
▸ ADK P55263 1/20 0.35
▸ NPC1 O15118 2/20 0.34
▸ RAB9A P51151 2/20 0.34
▸ TSHR P16473 2/20 0.34
▸ KMO O15229 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20137315 1.00 KMT2A (0.39) KMT2ASMN1; SMN2CYP1A2KDM4EMEN1
SCHEMBL29450666 1.00 KMT2A (0.39) KMT2ASMN1; SMN2CYP1A2KDM4EMEN1
SCHEMBL20137313 0.95 KMT2A (0.36) KMT2ASMN1; SMN2CYP1A2KDM4EMEN1
SCHEMBL29450675 0.95 KMT2A (0.36) KMT2ASMN1; SMN2CYP1A2KDM4EMEN1
SCHEMBL20137318 0.94 KMO (0.40) KMT2ASMN1; SMN2CYP1A2KDM4EMEN1
SCHEMBL20149263 0.94 PDK2 (0.34) KMT2ASMN1; SMN2CYP1A2KDM4EMEN1
SCHEMBL24646366 0.88 PDK2 (0.46) KMT2ASMN1; SMN2MEN1MAPTPDK2
SCHEMBL17153663 0.88 PDK2 (0.46) KMT2ASMN1; SMN2MEN1MAPTPDK2
SCHEMBL16366431 0.88 PDK2 (0.46) KMT2ASMN1; SMN2MEN1MAPTPDK2
SCHEMBL24647433 0.88 PDK2 (0.46) KMT2ASMN1; SMN2MEN1MAPTPDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10749112-B2 Light-emitting element, display device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-08-18 — — US disclosed
US-20190245146-A1 Light-Emitting Element, Display Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-08-08 — — US disclosed
US-10270039-B2 Light-emitting element, display device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-04-23 — — US disclosed
US-20180138416-A1 Light-Emitting Element, Display Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-05-17 — — US disclosed
US-20180138416-A1 Light-Emitting Element, Display Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-05-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180138416-A1 Light-Emitting Element, Display Device, Electronic Device, and Lighting Device ESR1, EHD1, PPOX KMT2A 2198/4885SMN1; SMN2 728/4885CYP1A2 1171/4885
US-10270039-B2 Light-emitting element, display device, electronic device, and lighting device ESR1, EHD1, PPOX KMT2A 2198/4885SMN1; SMN2 728/4885CYP1A2 1171/4885
US-20190245146-A1 Light-Emitting Element, Display Device, Electronic Device, and Lighting Device ESR1, EHD1, PPOX KMT2A 2198/4885SMN1; SMN2 728/4885CYP1A2 1171/4885
US-10749112-B2 Light-emitting element, display device, electronic device, and lighting device ESR1, EHD1, PPOX KMT2A 2198/4885SMN1; SMN2 728/4885CYP1A2 1171/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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