Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9389048 | 0.83 | PKM (0.40) | TDP1TSHRALOX5CASP1PKM | |
| SCHEMBL9971674 | 0.83 | CYP4F2 (0.49) | ALOX5NFKB1NFKB2RELASMN1; SMN2 | |
| SCHEMBL10015715 | 0.82 | ALOX5 (0.44) | TDP1ALOX5NFKB1NFKB2RELA | |
| SCHEMBL8751252 | 0.81 | ALOX5 (0.40) | TDP1ALOX5NFKB1NFKB2RELA | |
| SCHEMBL8137555 | 0.81 | ALOX5 (0.43) | TDP1ALOX5NFKB1NFKB2RELA | |
| SCHEMBL816093 | 0.80 | ALOX5 (0.49) | TSHRALOX5NFKB1NFKB2RELA | |
| SCHEMBL29327468 | 0.79 | TSHR (0.44) | TDP1TSHRALOX5CASP1PKM | |
| SCHEMBL26229210 | 0.78 | ALOX5 (0.43) | TDP1ALOX5NFKB1NFKB2RELA | |
| SCHEMBL11032834 | 0.78 | TDP1 (0.48) | TDP1ALOX5CASP1PKMSMN1; SMN2 | |
| SCHEMBL17260578 | 0.77 | DGKA (0.45) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180134836-A1 | POLYURETHANE COVERINGS HAVING REDUCED WATER ABSORPTION AND USE THEREOF | COVESTRO DEUTSCHLAND AG (DE) | 2018-05-17 | — | — | US | disclosed |