Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.62 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.62 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.62 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.62 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.62 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 5/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 2/20 | 0.43 |
| ▸ | MMP8 | P22894 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2011747 | 0.91 | ALDH1A1 (0.65) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL12629087 | 0.91 | ALDH1A1 (0.65) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL12629080 | 0.84 | ALDH1A1 (0.60) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2037755 | 0.84 | ALDH1A1 (0.58) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2011582 | 0.84 | ALDH1A1 (0.60) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5252168 | 0.82 | ALDH1A1 (1.00) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL12629084 | 0.82 | ALDH1A1 (0.66) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2017637 | 0.82 | ALDH1A1 (0.66) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL12629079 | 0.80 | ALDH1A1 (0.53) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL16917360 | 0.79 | NPSR1 (0.53) | ALDH1A1PSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011073269-A1 | PIPERIDINE ARYL SULFONAMIDE DERIVATIVES AS KV1.3 MODULATORS | EVOTEC AG (DE) | 2011-06-23 | — | — | WO | claimed |