SCHEMBL2013844

SCHEMBL2013844

Fc1cc(F)cc(-c2[c]cccc2C(F)(F)F)c1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2426847 0.86 CYP11B2 (0.43) CYP11B2
SCHEMBL2433532 0.84 NR1H2 (0.35) CYP11B2
SCHEMBL3021266 0.82 RXRA (0.35)
SCHEMBL17514475 0.81
SCHEMBL1369135 0.79 KIF11 (0.39) CYP11B2
SCHEMBL2357011 0.79 AHR (0.33)
SCHEMBL2431532 0.79 KIF11 (0.38) CYP11B2
SCHEMBL17514790 0.77 CYP1A1 (0.41) CYP11B2
SCHEMBL3829054 0.76 KIF11 (0.45)
SCHEMBL9586460 0.76 APP (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013182433-A1 A PROCESS USING GRIGNARD REAGENTS BASF SE (DE) 2013-12-12 WO disclosed
EP-2547687-A1 A PROCESS USING GRIGNARD REAGENTS BASF SE (DE) 2013-01-23 EP disclosed
EP-2513067-A1 METHOD FOR PRODUCING TRIAZOLINTHIONE DERIVATIVES AND INTERMEDIATES THEREOF BASF SE (DE) 2012-10-24 EP disclosed
WO-2011113820-A1 A PROCESS USING GRIGNARD REAGENTS BASF SE (DE) 2011-09-22 WO disclosed
WO-2011073145-A1 METHOD FOR PRODUCING TRIAZOLINTHIONE DERIVATIVES AND INTERMEDIATES THEREOF BASF SE (DE) 2011-06-23 WO disclosed