Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 2/20 | 0.59 |
| ▸ | TRPM8 | Q7Z2W7 | 12/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | PPARD | Q03181 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | TNKS | O95271 | 1/20 | 0.48 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL68542 | 0.82 | ALDH1A1 (0.63) | CCR3TRPM8ALDH1A1PPARGPPARD | |
| SCHEMBL27988120 | 0.81 | CCR3 (0.54) | CCR3TRPM8ALDH1A1PPARGPPARD | |
| SCHEMBL31005006 | 0.80 | ALDH1A1 (0.61) | CCR3TRPM8ALDH1A1PPARGPPARD | |
| Fluoride SCHEMBL28006168 | 0.80 | ALDH1A1 (0.61) | CCR3TRPM8ALDH1A1PPARGPPARD | |
| SCHEMBL16933701 | 0.78 | ALDH1A1 (0.50) | CCR3TRPM8ALDH1A1PPARGPPARD | |
| SCHEMBL16933899 | 0.78 | ALDH1A1 (0.50) | CCR3TRPM8ALDH1A1PPARGPPARD | |
| SCHEMBL17655660 | 0.77 | TNKS (0.59) | CCR3TRPM8ALDH1A1PPARGPPARD | |
| Rhaphidecursinol B SCHEMBL28577435 | 0.77 | CCR3 (0.86) | CCR3TRPM8TRPA1 | |
| Rhaphidecursinol B SCHEMBL28577433 | 0.77 | CCR3 (0.86) | CCR3TRPM8TRPA1 | |
| SCHEMBL3141953 | 0.76 | ALDH1A1 (0.56) | CCR3TRPM8ALDH1A1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180132516-A1 | POSITIVE ALLOSTERIC MODULATORS OF SWEET TASTE | SENSORYGEN INC (US) | 2018-05-17 | — | — | US | disclosed |