Rhaphidecursinol B

Rhaphidecursinol B

SCHEMBL28577433

C=CCc1cc(OC)c(O[C@H](C)[C@H](O)c2cc(OC)c(OC)c(OC)c2)c(OC)c1

nearest known ligand 0.86

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Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CCR3 P51677 2/20 0.86
TRPM8 Q7Z2W7 14/20 0.61
TRPA1 O75762 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Rhaphidecursinol B SCHEMBL28577435 1.00 CCR3 (0.86) CCR3TRPM8TRPA1
SCHEMBL29163797 0.93 CCR3 (0.82) CCR3TRPM8TRPA1
SCHEMBL27988447 0.89 CCR3 (0.76) CCR3TRPM8TRPA1
SCHEMBL30582656 0.87 TRPM8 (0.78) CCR3TRPM8TRPA1
SCHEMBL15004056 0.87 TRPM8 (0.78) CCR3TRPM8TRPA1
SCHEMBL16216996 0.81 TRPM8 (0.69) CCR3TRPM8TRPA1
SCHEMBL27988119 0.80 CCR3 (0.63) CCR3TRPM8TRPA1
SCHEMBL68542 0.80 ALDH1A1 (0.63) CCR3TRPM8
SCHEMBL13396022 0.79 ACHE (0.55) CCR3
SCHEMBL3410741 0.79 ACHE (0.55) CCR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109674774-B Application of propane-1-alcohol compound in preparation of medicine for treating cerebral hemorrhage 扬州大学 2021-06-25 CN claimed
CN-109674774-B Application of propane-1-alcohol compound in preparation of medicine for treating cerebral hemorrhage 扬州大学 2021-06-25 CN disclosed
CN-109674774-B Application of propane-1-alcohol compound in preparation of medicine for treating cerebral hemorrhage 扬州大学 2021-06-25 CN disclosed