SCHEMBL16933701

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL68542	0.87	ALDH1A1 (0.63)	ALDH1A1CCR3PPARGPPARDPPARA
	SCHEMBL31005006	0.85	ALDH1A1 (0.61)	ALDH1A1CCR3PPARGPPARDPPARA
	Fluoride SCHEMBL28006168	0.85	ALDH1A1 (0.61)	ALDH1A1CCR3PPARGPPARDPPARA
	SCHEMBL16933899	0.84	ALDH1A1 (0.50)	ALDH1A1CCR3PPARGPPARDPPARA
	SCHEMBL15867159	0.81	ALDH1A1 (0.73)	ALDH1A1PPARGPPARDPPARATRPM8
	SCHEMBL29582029	0.79	ALDH1A1 (0.51)	ALDH1A1CCR3PPARGPPARDPPARA
	SCHEMBL27988120	0.79	CCR3 (0.54)	ALDH1A1CCR3PPARGPPARDPPARA
	SCHEMBL17655660	0.78	TNKS (0.59)	ALDH1A1CCR3PPARGPPARDPPARA
	SCHEMBL20138466	0.78	CCR3 (0.59)	ALDH1A1CCR3PPARGPPARDPPARA
	SCHEMBL3141953	0.77	ALDH1A1 (0.56)	ALDH1A1CCR3PPARGPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.