Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | SCN1A | P35498 | 1/20 | 0.50 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.50 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25416177 | 0.88 | MEN1 (0.53) | KMT2ALMNACYP2D6MEN1HRH1 | |
| SCHEMBL5049560 | 0.87 | KEAP1 (0.49) | KMT2ACYP2D6MAPTCHRM3CHRM2 | |
| SCHEMBL5049483 | 0.85 | KEAP1 (0.47) | KMT2ACYP2D6MEN1MAPTCHRM3 | |
| SCHEMBL27934877 | 0.81 | MEN1 (0.36) | KMT2ALMNACYP2D6MEN1HRH1 | |
| SCHEMBL8129248 | 0.81 | MEN1 (0.51) | KMT2ALMNACYP2D6MEN1HRH1 | |
| SCHEMBL5161856 | 0.79 | MAPT (0.49) | MAPT | |
| SCHEMBL30874977 | 0.79 | OPRD1 (0.34) | KMT2ALMNACYP2D6MEN1HRH1 | |
| SCHEMBL27626467 | 0.78 | KMT2A (0.54) | KMT2ALMNACYP2D6MEN1HRH1 | |
| SCHEMBL959566 | 0.77 | KMT2A (0.57) | KMT2ALMNACYP2D6MEN1HRH1 | |
| SCHEMBL31347956 | 0.75 | CYP2D6 (0.41) | KMT2ALMNACYP2D6MEN1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180132516-A1 | POSITIVE ALLOSTERIC MODULATORS OF SWEET TASTE | SENSORYGEN INC (US) | 2018-05-17 | — | — | US | disclosed |
| CN-1671386-A | Substituted anilinic piperidines as MCH selective antagonists | LUNDBECK & CO AS H (DK) | 2005-09-21 | — | — | CN | disclosed |