Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 5/20 | 0.43 |
| ▸ | HTR2C | P28335 | 5/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.43 |
| ▸ | HTR1D | P28221 | 2/20 | 0.43 |
| ▸ | HTR1B | P28222 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5155747 | 0.80 | HPGD (0.50) | ATMCYP3A4GPR84MEN1MAPT | |
| SCHEMBL18180510 | 0.78 | ALDH1A1 (0.46) | ATMCYP3A4GPR84MEN1MAPT | |
| SCHEMBL27125656 | 0.77 | IDO1 (0.51) | ATMMEN1MAPTKMT2ATDP1 | |
| SCHEMBL18160175 | 0.77 | IDO1 (0.51) | ATMMEN1MAPTKMT2ATDP1 | |
| SCHEMBL18463827 | 0.76 | PTPN11 (0.54) | ATMCYP3A4GPR84MEN1MAPT | |
| SCHEMBL11664491 | 0.75 | ATM (0.54) | ATMCYP3A4GPR84MEN1MAPT | |
| SCHEMBL7363256 | 0.75 | HPGD (0.48) | ATMCYP3A4GPR84MEN1MAPT | |
| SCHEMBL17919422 | 0.75 | ATM (0.48) | ATMCYP3A4GPR84MEN1MAPT | |
| SCHEMBL724284 | 0.75 | ATM (0.54) | ATMCYP3A4GPR84MEN1MAPT | |
| SCHEMBL5514930 | 0.74 | GPR84 (0.49) | ATMCYP3A4GPR84MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019190354-A1 | PHENYLFORMAMIDINE DERIVATIVES HAVING ANTIMYCOBACTERIAL ACTIVITY | ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "МТ-МЕДИКАЛС" | 2019-10-03 | — | — | WO | disclosed |
| WO-2018088920-A1 | 3-TRIAZENOINDOLES EXHIBITING ANTIMYCOBACTERIAL ACTIVITY | АПТ, Александр Соломонович | 2018-05-17 | — | — | WO | disclosed |