Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.48 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.44 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | PRKCG | P05129 | 1/20 | 0.44 |
| ▸ | PRKCB | P05771 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17919422 | 0.78 | ATM (0.48) | HPGDHTTGPR84IMPDH2CYP2A6 | |
| SCHEMBL11664491 | 0.78 | ATM (0.54) | HPGDHTTGPR84IMPDH2CYP2A6 | |
| SCHEMBL724284 | 0.78 | ATM (0.54) | HPGDHTTGPR84IMPDH2CYP2A6 | |
| SCHEMBL4042175 | 0.78 | IMPDH2 (0.44) | HPGDHTTGPR84IMPDH2CYP2A6 | |
| SCHEMBL30089259 | 0.78 | IMPDH2 (0.44) | HPGDHTTGPR84IMPDH2CYP2A6 | |
| SCHEMBL3456817 | 0.76 | GPR84 (0.52) | HPGDGPR84ATMMEN1MAPT | |
| SCHEMBL20138600 | 0.75 | ATM (0.45) | HPGDHTTGPR84IMPDH2CYP2A6 | |
| SCHEMBL5155747 | 0.75 | HPGD (0.50) | HPGDHTTGPR84IMPDH2CYP2A6 | |
| SCHEMBL5515060 | 0.75 | ALDH1A1 (0.56) | HPGDHTTGPR84IMPDH2CYP2A6 | |
| SCHEMBL927315 | 0.74 | ATP4A (0.52) | HPGDHTTGPR84IMPDH2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111662299-B | Substituted indolocazazepine compound and preparation method and application thereof | 中山大学 | 2022-07-26 | — | — | CN | claimed |
| CN-109535061-B | 3-nitrosoindole derivative and preparation method thereof | 苏州大学 | 2020-07-14 | — | — | CN | claimed |
| CN-109535061-A | A kind of 3- nitroso-indol derivative and preparation method thereof | 苏州大学 | 2019-03-29 | — | — | CN | claimed |
| CN-108350499-A | Convertible marking compositions, methods, and processes incorporating same | 10X基因组学有限公司 | 2018-07-31 | — | — | CN | claimed |
| US-4380629-A | Styryl-like compounds showing a color-developing and bleaching behavior with improved stability and prolonged lifetime | MATSUSHITA ELECTRIC INDUSTRIAL COMPANY, LIMITED (JP) | 1983-04-19 | — | — | US | claimed |
| US-4314058-A | Indolins styryl-like compounds | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1982-02-02 | — | — | US | claimed |
| US-4147862-A | Method of preparing styryl-like compounds | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1979-04-03 | — | — | US | claimed |
| CN-119031945-A | Method for detecting indole, indole-producing bacteria or indole-producing chemicals | 密歇根大学董事会 | 2024-11-26 | — | — | CN | disclosed |
| US-11639347-B2 | Modulators of ATP-binding cassette transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-05-02 | — | — | US | disclosed |
| US-20230127655-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-04-27 | — | — | US | disclosed |
| US-20220411410-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED | 2022-12-29 | — | — | US | disclosed |
| WO-2021023888-A1 | ISOQUINOLINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | B.C.I. PHARMA (BE) | 2021-02-11 | — | — | WO | disclosed |
| CN-109535061-B | 3-nitrosoindole derivative and preparation method thereof | 苏州大学 | 2020-07-14 | — | — | CN | disclosed |
| EP-0509402-A1 | Substituted 3-(Pyridinylamino)-indoles and benzo[b]thiophenes, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-10-21 | — | — | EP | disclosed |
| US-4380629-A | Styryl-like compounds showing a color-developing and bleaching behavior with improved stability and prolonged lifetime | MATSUSHITA ELECTRIC INDUSTRIAL COMPANY, LIMITED (JP) | 1983-04-19 | — | — | US | disclosed |
| US-4340624-A | STYRYL-LIKE COMPOUNDS | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1982-07-20 | — | — | US | disclosed |
| US-4314058-A | Indolins styryl-like compounds | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1982-02-02 | — | — | US | disclosed |
| US-4147862-A | Method of preparing styryl-like compounds | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1979-04-03 | — | — | US | disclosed |
| US-4139274-A | Apparatus for changing color | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1979-02-13 | — | — | US | disclosed |
| US-4003633-A | Color display device | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JA) | 1977-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220411410-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | CFTR, ABCB1, ABCC2 | HPGD 1644/4885HTT 1077/4885GPR84 409/4885 |
| US-11639347-B2 | Modulators of ATP-binding cassette transporters | CFTR, ABCB1, ABCC2 | HPGD 1644/4885HTT 1077/4885GPR84 409/4885 |
| US-20230127655-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | CFTR, ABCB1, ABCC2 | HPGD 1644/4885HTT 1077/4885GPR84 409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.