Glycerin

Glycerin

SCHEMBL20138604

CC(N)=O.CCOCC.OCC(O)CO

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.41
ALDH1A1 P00352 4/20 0.41
ALOX15 P16050 2/20 0.37
TSHR P16473 1/20 0.37
BLM P54132 1/20 0.36
PMP22 Q01453 1/20 0.36
USP2 O75604 1/20 0.35
KDM4E B2RXH2 1/20 0.35
DUSP3 P51452 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
PLA2G2C Q5R387 1/20 0.34
HSD17B10 Q99714 1/20 0.33
THRB P10828 1/20 0.32
DGKA P23743 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycerin SCHEMBL4322656 0.88 ALDH1A1 (0.43) LMNAALDH1A1TSHRUSP2KDM4E
Glycerin SCHEMBL14658419 0.86 ALDH1A1 (0.45) LMNAALDH1A1TSHRUSP2KDM4E
Glycerin SCHEMBL19182834 0.85 LMNA (0.56) LMNAALDH1A1ALOX15BLMPMP22
Glycerin SCHEMBL8080968 0.85 LMNA (0.56) LMNAALDH1A1TSHRUSP2KDM4E
Glycerin SCHEMBL6426113 0.85 LMNA (0.56) LMNAALDH1A1TSHRUSP2KDM4E
Glycerin SCHEMBL30753 0.85 LMNA (0.56) LMNAALDH1A1TSHRUSP2KDM4E
Glycerin SCHEMBL490858 0.85 LMNA (0.56) LMNAALDH1A1TSHRUSP2KDM4E
Glycerin SCHEMBL11595153 0.83 LMNA (0.53) LMNAALDH1A1TSHRUSP2KDM4E
Glycerin SCHEMBL4723284 0.83 LMNA (0.53) LMNAALDH1A1TSHRUSP2KDM4E
Ether SCHEMBL442290 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3539964-B1 BASE ACETAMIDE GLYCERIN ETHER MOLECULE, CHEMICAL SYNTHESIS METHOD THEREFOR, AND APPLICATIONS THEREOF IN FIELD OF GENE THERAPY BEIJING INTELLIGENE BIOTECH LTD CO (CN) 2021-11-10 EP claimed
CN-108059619-B A kind of base acetamide glycerin ether molecule, chemical synthesis process and its application in field of gene 北京大学 2019-10-25 CN claimed
EP-3539964-A1 BASE ACETAMIDE GLYCERIN ETHER MOLECULE, CHEMICAL SYNTHESIS METHOD THEREFOR, AND APPLICATIONS THEREOF IN FIELD OF GENE THERAPY Peking University (CN) 2019-09-18 EP claimed
CN-108059619-A A kind of base acetamide glycerin ether molecule, chemical synthesis process and its application in field of gene 北京大学 2018-05-22 CN claimed
EP-3539964-B1 BASE ACETAMIDE GLYCERIN ETHER MOLECULE, CHEMICAL SYNTHESIS METHOD THEREFOR, AND APPLICATIONS THEREOF IN FIELD OF GENE THERAPY BEIJING INTELLIGENE BIOTECH LTD CO (CN) 2021-11-10 EP disclosed
EP-3539964-B1 BASE ACETAMIDE GLYCERIN ETHER MOLECULE, CHEMICAL SYNTHESIS METHOD THEREFOR, AND APPLICATIONS THEREOF IN FIELD OF GENE THERAPY BEIJING INTELLIGENE BIOTECH LTD CO (CN) 2021-11-10 EP disclosed
EP-3539964-A4 BASE ACETAMIDE GLYCERIN ETHER MOLECULE, CHEMICAL SYNTHESIS METHOD THEREFOR, AND APPLICATIONS THEREOF IN FIELD OF GENE THERAPY Peking University (CN) 2020-05-27 EP disclosed
CN-108059619-B A kind of base acetamide glycerin ether molecule, chemical synthesis process and its application in field of gene 北京大学 2019-10-25 CN disclosed
CN-108059619-B A kind of base acetamide glycerin ether molecule, chemical synthesis process and its application in field of gene 北京大学 2019-10-25 CN disclosed
CN-108059619-B A kind of base acetamide glycerin ether molecule, chemical synthesis process and its application in field of gene 北京大学 2019-10-25 CN disclosed
EP-3539964-A1 BASE ACETAMIDE GLYCERIN ETHER MOLECULE, CHEMICAL SYNTHESIS METHOD THEREFOR, AND APPLICATIONS THEREOF IN FIELD OF GENE THERAPY Peking University (CN) 2019-09-18 EP disclosed
EP-3539964-A1 BASE ACETAMIDE GLYCERIN ETHER MOLECULE, CHEMICAL SYNTHESIS METHOD THEREFOR, AND APPLICATIONS THEREOF IN FIELD OF GENE THERAPY Peking University (CN) 2019-09-18 EP disclosed
EP-3539964-A1 BASE ACETAMIDE GLYCERIN ETHER MOLECULE, CHEMICAL SYNTHESIS METHOD THEREFOR, AND APPLICATIONS THEREOF IN FIELD OF GENE THERAPY Peking University (CN) 2019-09-18 EP disclosed
CN-108478807-A A kind of nucleic acid drug delivery system and its application 北京大学 2018-09-04 CN disclosed
CN-108059619-A A kind of base acetamide glycerin ether molecule, chemical synthesis process and its application in field of gene 北京大学 2018-05-22 CN disclosed
CN-108059619-A A kind of base acetamide glycerin ether molecule, chemical synthesis process and its application in field of gene 北京大学 2018-05-22 CN disclosed
CN-108059619-A A kind of base acetamide glycerin ether molecule, chemical synthesis process and its application in field of gene 北京大学 2018-05-22 CN disclosed
WO-2018085962-A1 BASE ACETAMIDE GLYCERIN ETHER MOLECULE, CHEMICAL SYNTHESIS METHOD THEREFOR, AND APPLICATIONS THEREOF IN FIELD OF GENE THERAPY 北京大学 2018-05-17 WO disclosed
WO-2018085962-A1 BASE ACETAMIDE GLYCERIN ETHER MOLECULE, CHEMICAL SYNTHESIS METHOD THEREFOR, AND APPLICATIONS THEREOF IN FIELD OF GENE THERAPY 北京大学 2018-05-17 WO disclosed